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Signatures of selection in the genome of Swedish warmblood horses selected for sport performance
- Source :
- BMC Genomics, Vol 20, Iss 1, Pp 1-12 (2019), BMC Genomics
- Publication Year :
- 2019
- Publisher :
- BMC, 2019.
-
Abstract
- Background A growing demand for improved physical skills and mental attitude in modern sport horses has led to strong selection for performance in many warmblood studbooks. The aim of this study was to detect genomic regions with low diversity, and therefore potentially under selection, in Swedish Warmblood horses (SWB) by analysing high-density SNP data. To investigate if such signatures could be the result of selection for equestrian sport performance, we compared our SWB SNP data with those from Exmoor ponies, a horse breed not selected for sport performance traits. Results The genomic scan for homozygous regions identified long runs of homozygosity (ROH) shared by more than 85% of the genotyped SWB individuals. Such ROH were located on ECA4, ECA6, ECA7, ECA10 and ECA17. Long ROH were instead distributed evenly across the genome of Exmoor ponies in 77% of the chromosomes. Two population differentiation tests (FST and XP-EHH) revealed signatures of selection on ECA1, ECA4, and ECA6 in SWB horses. Conclusions Genes related to behaviour, physical abilities and fertility, appear to be targets of selection in the SWB breed. This study provides a genome-wide map of selection signatures in SWB horses, and ground for further functional studies to unravel the biological mechanisms behind complex traits in horses.
- Subjects :
- Male
Genotyping Techniques
Performance
DIVERSITY
Breeding
Runs of Homozygosity
Horse
Genome
HISTORY
Inbreeding
HOMOZYGOSITY
Genetics & Heredity
0303 health sciences
Snp data
education.field_of_study
Homozygote
RUNS
ASSOCIATION
Genomics
04 agricultural and veterinary sciences
Breed
DIFFERENTIATION
Warmblood
Female
Life Sciences & Biomedicine
TRAITS
Research Article
Sports
Biotechnology
GENES
lcsh:QH426-470
lcsh:Biotechnology
Population
Biology
Runs of homozygosity
Polymorphism, Single Nucleotide
03 medical and health sciences
lcsh:TP248.13-248.65
Genetics
Animals
Horses
Functional studies
education
Selection (genetic algorithm)
030304 developmental biology
Science & Technology
0402 animal and dairy science
Selection signature
040201 dairy & animal science
lcsh:Genetics
Biotechnology & Applied Microbiology
Evolutionary biology
WIDE SCAN
Haplotype homozygosity
Subjects
Details
- Language :
- English
- ISSN :
- 14712164
- Volume :
- 20
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- BMC Genomics
- Accession number :
- edsair.doi.dedup.....d49a050fc82608f94450991b331ac102