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Clinical Outcome of Twice-Weekly Hemodialysis Patients with Long-Term Dialysis Vintage
- Source :
- Kidney & Blood Pressure Research, Vol 43, Iss 4, Pp 1104-1112 (2018)
- Publication Year :
- 2018
-
Abstract
- Background/Aims: Twice-weekly hemodialysis(HD) is prevalent in the developing countries, scarce data are available for this treatment in patients with long-term dialysis vintage. Methods: 106 patients with more than 5 years HD vintage undergoing twice-weekly HD or thrice-weekly HD in a hemodialysis center in Shanghai between December 1, 2013 and December 31, 2013 were enrolled into the cohort study with 3 years follow-up. Kaplan–Meier analysis and Cox proportional hazards models were used to compare patient survival between the two groups. Subgroup analysis of 62 patients more than 10 years HD vintage was also performed according to their different dialysis frequency. Results: Compared with patients on thrice-weekly HD, twice-weekly HD patients had significantly longer HD session time and higher single-pool Kt/V (spKt/V) (session time, 4.59±0.45 vs 4.14±0.31 hours/per session, P< 0.001; spKt/V, 2.12±0.31 vs 1.83±0.30, P< 0.001). Kaplan–Meier survival analysis indicated that the two groups had similar survival (P=0.983). Multivariate Cox regression analysis showed that age and time-dependent serum albumin were predictors of patient mortality. Subgroup analysis of 62 patients more than 10 years HD vintage also indicated that the two groups had similar survival. During the follow-up, 4 patients dropped out from the twice-weekly HD group and transferred to thrice-weekly HD. Conclusion: The similar survival between twice-weekly HD and thrice-weekly HD in patients with long-term dialysis vintage is likely relating to patient selection, individualized treatment for dialysis patients based on clinical features and socioeconomic factors remains a tough task for the clinicians.
- Subjects :
- Vintage
Male
medicine.medical_specialty
lcsh:Diseases of the circulatory (Cardiovascular) system
China
Survival
medicine.medical_treatment
030232 urology & nephrology
Subgroup analysis
Kaplan-Meier Estimate
030204 cardiovascular system & hematology
lcsh:RC870-923
03 medical and health sciences
0302 clinical medicine
Renal Dialysis
Internal medicine
lcsh:Dermatology
Medicine
Humans
Dialysis
Survival analysis
Dialysis frequency
Serum Albumin
Aged
Proportional Hazards Models
Retrospective Studies
Proportional hazards model
business.industry
Long term dialysis
Age Factors
General Medicine
lcsh:RL1-803
Middle Aged
lcsh:Diseases of the genitourinary system. Urology
Nephrology
lcsh:RC666-701
Hemodialysis
Kidney Failure, Chronic
Female
Cardiology and Cardiovascular Medicine
business
Cohort study
Subjects
Details
- ISSN :
- 14230143
- Volume :
- 43
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Kidneyblood pressure research
- Accession number :
- edsair.doi.dedup.....d4d9928da67a13489617438ed9de4190