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Clinical outcomes following the surgery of new autologous arteriovenous fistulas proximal to the failed ones in end-stage renal disease patients: a retrospective cohort study
- Source :
- Renal Failure, Renal Failure, Vol 41, Iss 1, Pp 1036-1044 (2019)
- Publication Year :
- 2019
- Publisher :
- Taylor & Francis, 2019.
-
Abstract
- Background: Most prior studies have explored surgery for the treatment of failed autologous arteriovenous fistulas (AVFs) with limited follow-up times and a lack of end point mortality. Accordingly, we conducted a retrospective cohort study to evaluate the clinical outcomes of the surgery of new AVF proximal to the failed forearm AVF. Methods: In this study, 538 end-stage renal disease patients (group A, 418 with primary AVF; and group B, 120 with failed AVF) were consecutively enrolled between January 2013 and June 2016, with a median follow-up time of 41 months. Primary and secondary patency, all-cause mortality, and risk factors associated with AVF failure were explored by the Kaplan–Meier method or Cox proportional hazards model. Results: In group A (n = 418), the primary and secondary patencies of AVF were 85.6% vs. 96.8%, 79.7% vs. 95.0%, 75.1% vs.93.9%, 73.2% vs. 93.6% and 73.2% vs. 93.6% at 12, 24, 36, 48 and 60 months, respectively. The primary patencies of AVF in group B were 95.0%, 91.7%, 89.2%, 88.3% and 88.3% at 12, 24, 36, 48 and 60 months, respectively. After adjusting for potential confounders, age, angiotensin-converting inhibitors or angiotensin-receptor blockers (anti-RAAS) drugs and D-dimer were independent predictors of AVF failure. However, there were no differences between functional and failed AVF regarding all-cause mortality. Conclusions: The study revealed that the primary and secondary patiencies of the surgery of new AVF proximal to the failed ones were ideal operations to restore failed forearm AVF.
- Subjects :
- Adult
Male
Reoperation
medicine.medical_specialty
congenital, hereditary, and neonatal diseases and abnormalities
China
Adolescent
030232 urology & nephrology
030204 cardiovascular system & hematology
Critical Care and Intensive Care Medicine
Autologous arteriovenous fistula
End stage renal disease
surgery
03 medical and health sciences
Young Adult
0302 clinical medicine
Arteriovenous Shunt, Surgical
medicine
Humans
cardiovascular diseases
Treatment Failure
Aged
Retrospective Studies
Aged, 80 and over
End point
business.industry
Retrospective cohort study
General Medicine
Middle Aged
mortality
Diseases of the genitourinary system. Urology
Surgery
Nephrology
Clinical Study
Kidney Failure, Chronic
Female
RC870-923
prognosis
business
Subjects
Details
- Language :
- English
- ISSN :
- 15256049 and 0886022X
- Volume :
- 41
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Renal Failure
- Accession number :
- edsair.doi.dedup.....d4f539262fd656b7f28fbfcf56a7cc32