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Comparative transcriptome profiling provides new insights into mechanisms of androgenetic alopecia progression
- Source :
- The British journal of dermatology. 176(1)
- Publication Year :
- 2016
-
Abstract
- Androgenetic alopecia (AGA) is the most common progressive form of hair loss that occurs in more than half of men above 50 years 1. AGA onset is dependent on genetic predisposition and presence of androgen 2, 3. In AGA patients, hair undergoes shortened anagen phase, progressive miniaturization and subsequent vellus transformation of terminal hair follicle. This article is protected by copyright. All rights reserved.
- Subjects :
- 0301 basic medicine
Adult
Male
medicine.medical_specialty
medicine.drug_class
education
Dermatology
Terminal hair
Biology
030207 dermatology & venereal diseases
03 medical and health sciences
Follicle
Young Adult
0302 clinical medicine
Internal medicine
medicine
Genetic predisposition
Transcriptome profiling
Humans
reproductive and urinary physiology
Aged
integumentary system
Gene Expression Profiling
Oxidation reduction
Alopecia
Middle Aged
Androgen
medicine.disease
female genital diseases and pregnancy complications
Up-Regulation
body regions
030104 developmental biology
Endocrinology
Hair loss
Case-Control Studies
Vellus hair
Cancer research
Disease Progression
Hair Follicle
Oxidation-Reduction
Subjects
Details
- ISSN :
- 13652133
- Volume :
- 176
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- The British journal of dermatology
- Accession number :
- edsair.doi.dedup.....d5305698002bf0e39ba0b1a42412b00e