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A novel assessment of local impedance during catheter ablation: initial experience in humans comparing local and generator measurements

Authors :
Ruken Ö. Akbulak
Paula Münkler
Christian Meyer
Christian Eickholt
Christiane Jungen
Melanie Gunawardene
Lydia Merbold
Mario Jularic
Leon Dinshaw
Niklas Klatt
Stephan Willems
Julia Moser
Jens Hartmann
Source :
EP Europace. 21:i34-i42
Publication Year :
2019
Publisher :
Oxford University Press (OUP), 2019.

Abstract

AIMS A novel measure of local impedance (LI) has been found to predict lesion formation during radiofrequency current (RFC) catheter ablation. The aim of this study was to investigate the utility of this novel approach, while comparing LI to the well-established generator impedance (GI). METHODS AND RESULTS In 25 consecutive patients with a history of atrial fibrillation, catheter ablation was guided by a 3D-mapping system measuring LI in addition to GI via an ablation catheter tip with three incorporated mini-electrodes. Local impedance and GI before and during RFC applications were studied. In total, 381 RFC applications were analysed. The baseline LI was higher in high-voltage areas (>0.5 mV; LI: 110.5 ± 13.7 Ω) when compared with intermediate-voltage sites (0.1-0.5 mV; 90.9 ± 10.1 Ω, P < 0.001), low-voltage areas (

Details

ISSN :
15322092 and 10995129
Volume :
21
Database :
OpenAIRE
Journal :
EP Europace
Accession number :
edsair.doi.dedup.....d5714c89ded65bf3eb5b274e9bd6e58b