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Triggers of breathlessness in inducible laryngeal obstruction and asthma
- Source :
- Haines, J, Chua, S H, Smith, J, Slinger, C, Simpson, A J & Fowler, S J 2020, ' Triggers of Breathlessness in Inducible Laryngeal Obstruction and Asthma ', Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology . https://doi.org/10.1111/cea.13715
- Publication Year :
- 2020
-
Abstract
- Background Inducible laryngeal obstruction (ILO) is often misdiagnosed as, or may coexist with, asthma. Identifying differences in triggering factors may assist clinicians to differentiate between the two conditions, and could give mechanistic insights. Objective To identify and compare patient‐reported triggers in ILO and asthma. Methods This was a two‐part study. Initially we conducted a retrospective case note review of the triggers of ILO from endoscopically‐confirmed ILO patients to generate a Breathlessness Triggers Survey (BrTS). Triggers were categorised as: scents, environmental factors, temperature, emotions, mechanical factors and daily activities. Secondly, ILO and/or asthma patients completed the BrTS prospectively, rating the likelihood of each item triggering their symptoms using a five‐point Likert scale (strongly disagree to strongly agree). Chi‐square testing was performed to compare responses by cohort. Results Data from 202 patients with ILO [73% female, mean (SD) age 53(16) years] were included in the case note review. For the prospective study, 38 patients with ILO‐only [63% females, age 57(16) years], 39 patients with asthma‐only [(56% female, age 53(13) years] and 12 patients with both ILO and asthma [83% female, mean age, 57 (14) years)] completed the BrTS. The triggers identified in the case note review were confirmed in the independent sample of patients with ILO and/or asthma and identified several difference in prevalence of the triggers between disease types. Mechanical factors [talking (p
- Subjects :
- 0301 basic medicine
Adult
Male
medicine.medical_specialty
Activities of daily living
Immunology
Disease
Comorbidity
Diagnosis, Differential
Laryngeal Diseases
03 medical and health sciences
0302 clinical medicine
Predictive Value of Tests
Risk Factors
Internal medicine
medicine
Immunology and Allergy
Humans
Prospective Studies
Prospective cohort study
Lung
Asthma
Aged
Retrospective Studies
business.industry
Mean age
Environmental Exposure
respiratory system
Middle Aged
medicine.disease
Laryngeal Obstruction
respiratory tract diseases
Airway Obstruction
030104 developmental biology
Dyspnea
030228 respiratory system
Cohort
Case note
Female
Self Report
business
Subjects
Details
- ISSN :
- 13652222
- Volume :
- 50
- Issue :
- 11
- Database :
- OpenAIRE
- Journal :
- Clinical and experimental allergy : journal of the British Society for Allergy and Clinical ImmunologyREFERENCES
- Accession number :
- edsair.doi.dedup.....d5737824b4764bc70e4a5a99711d0dc7