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Traditional Chinese Medicine Formulation Therapy in the Treatment of Coronavirus Disease 2019 (COVID-19)

Authors :
Keshan Yin
Jing Zhang
Lu Xia
Zongguo Yang
Jia Shi
Yuan Zhang
Xiaorong Chen
Ying Lü
Qingnian Xu
Bozong Tang
Shishi Chen
Yunfei Lu
Chen Ye
Source :
The American Journal of Chinese Medicine
Publication Year :
2020
Publisher :
World Scientific Pub Co Pte Lt, 2020.

Abstract

This study aimed to investigate the efficacy of Traditional Chinese Medicine (TCM) decoction with different intervention timepoints in the treatment of coronavirus disease 2019 (COVID-19) patients. We retrospectively collected the medical records and evaluated the outcomes of COVID-19 patients that received TCM decoction treatment at different timepoints. A total of 234 COVID-19 patients were included in this study. Patients who received TCM decoction therapy within 3 days or 7 days after admission could achieve shorter hospitalization days and disease periods compared to those who received TCM decoction [Formula: see text] 7 days after admission (all [Formula: see text]). Patients who received TCM decoction therapy within 3 days had significantly fewer days to negative SARS-CoV-2 from nasopharyngeal/oral swab and days to negative SARS-CoV-2 from urine/stool/blood samples compared to those received TCM decoction [Formula: see text] days after admission (all [Formula: see text]). Patients who received TCM decoction therapy on the 3rd to 7th day after admission had a faster achievement of negative SARS-CoV-2 from urine/stool/blood samples compared to those who received TCM decoction [Formula: see text] days after admission ([Formula: see text]). Logistic models revealed that more days from TCM decoction to admission [Formula: see text] days might be a risk factor for long hospitalization days, disease period, and slower negative-conversion of SARS-CoV-2 (all [Formula: see text]). Conclusively, our results suggest that TCM decoction therapy should be considered at the early stage of COVID-19 patients.

Details

Language :
English
ISSN :
17936853 and 0192415X
Database :
OpenAIRE
Journal :
The American Journal of Chinese Medicine
Accession number :
edsair.doi.dedup.....d593a534523c6c0f34617c2fccfdddd2
Full Text :
https://doi.org/10.1142/s0192415x20500755