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Traditional Chinese Medicine Formulation Therapy in the Treatment of Coronavirus Disease 2019 (COVID-19)
- Source :
- The American Journal of Chinese Medicine
- Publication Year :
- 2020
- Publisher :
- World Scientific Pub Co Pte Lt, 2020.
-
Abstract
- This study aimed to investigate the efficacy of Traditional Chinese Medicine (TCM) decoction with different intervention timepoints in the treatment of coronavirus disease 2019 (COVID-19) patients. We retrospectively collected the medical records and evaluated the outcomes of COVID-19 patients that received TCM decoction treatment at different timepoints. A total of 234 COVID-19 patients were included in this study. Patients who received TCM decoction therapy within 3 days or 7 days after admission could achieve shorter hospitalization days and disease periods compared to those who received TCM decoction [Formula: see text] 7 days after admission (all [Formula: see text]). Patients who received TCM decoction therapy within 3 days had significantly fewer days to negative SARS-CoV-2 from nasopharyngeal/oral swab and days to negative SARS-CoV-2 from urine/stool/blood samples compared to those received TCM decoction [Formula: see text] days after admission (all [Formula: see text]). Patients who received TCM decoction therapy on the 3rd to 7th day after admission had a faster achievement of negative SARS-CoV-2 from urine/stool/blood samples compared to those who received TCM decoction [Formula: see text] days after admission ([Formula: see text]). Logistic models revealed that more days from TCM decoction to admission [Formula: see text] days might be a risk factor for long hospitalization days, disease period, and slower negative-conversion of SARS-CoV-2 (all [Formula: see text]). Conclusively, our results suggest that TCM decoction therapy should be considered at the early stage of COVID-19 patients.
- Subjects :
- 0301 basic medicine
Adult
Male
medicine.medical_specialty
Decoction
Traditional Chinese medicine
Urine
03 medical and health sciences
0302 clinical medicine
Pharmacotherapy
Internal medicine
Medicine
Humans
Traditional Chinese Medicine Formulation
Risk factor
Medicine, Chinese Traditional
Pandemics
Aged
Retrospective Studies
business.industry
SARS-CoV-2
Medical record
COVID-19
Retrospective cohort study
General Medicine
Length of Stay
Middle Aged
COVID-19 Drug Treatment
030104 developmental biology
Treatment Outcome
Complementary and alternative medicine
030220 oncology & carcinogenesis
Female
business
Drugs, Chinese Herbal
Subjects
Details
- Language :
- English
- ISSN :
- 17936853 and 0192415X
- Database :
- OpenAIRE
- Journal :
- The American Journal of Chinese Medicine
- Accession number :
- edsair.doi.dedup.....d593a534523c6c0f34617c2fccfdddd2
- Full Text :
- https://doi.org/10.1142/s0192415x20500755