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Histopathological changes in parotid gland following submandibular gland failure: an experimental animal study
- Source :
- Brazilian Journal of Otorhinolaryngology, Vol 85, Iss 4, Pp 422-426 (2019), Brazilian Journal of Otorhinolaryngology v.85 n.4 2019, Brazilian Journal of Otorhinolaryngology, Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF), instacron:ABORL-CCF, Brazilian Journal of Otorhinolaryngology, Volume: 85, Issue: 4, Pages: 422-426, Published: 29 AUG 2019
- Publication Year :
- 2019
- Publisher :
- Elsevier, 2019.
-
Abstract
- Introduction: Submandibular glands are exposed to many effects due to diseases and therapeutic interventions. A study evaluating the effect of submandibular gland dysfunction on the parotid gland has not been presented in the literature. Objective: The aim of this study was to evaluate the histopathological changes in the parotid gland following submandibular gland failure. Methods: Three groups of seven randomly selected female New Zealand rabbits weighing 2500–3000 g were studied. Unilateral and bilateral submandibular glands were removed in Groups 1 and 2, respectively. No procedure was performed in Group III, the control group. The parotid glands were removed 30 days later. Histological parameters were evaluated and graded between 0 (none) and 3 (severe). Differences between groups were compared using the Mann–Whitney U test. Results: Mean mucus accumulation in acinar cells was 2.57 ± 0.53 and 1.71 ± 0.75 in Groups 1 and 2, respectively (p 0.05). This value was 0.28 ± 0.48 in Group 3, which was significantly lower than in Groups 1 and 2 (p 0,05). Esse valor foi de 0,28 ± 0,48 no Grupo 3, significativamente menor do que nos Grupos 1 e 2 (p
- Subjects :
- Submandibular
Pathology
medicine.medical_specialty
Submandibular Gland
Lumen (anatomy)
Histopathology
Acinar Cells
030218 nuclear medicine & medical imaging
03 medical and health sciences
0302 clinical medicine
stomatognathic system
medicine
Animals
Parotid Gland
Parotid
business.industry
Parótida
lcsh:Otorhinolaryngology
Submandibular gland
Mucus
lcsh:RF1-547
Parotid gland
Histopatologia
Experimental animal
medicine.anatomical_structure
Otorhinolaryngology
Models, Animal
Female
Rabbits
Insuficiência da glândula submandibular
Submandibular gland failure
business
030217 neurology & neurosurgery
Subjects
Details
- Language :
- English
- ISSN :
- 18088694
- Volume :
- 85
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Brazilian Journal of Otorhinolaryngology
- Accession number :
- edsair.doi.dedup.....d5c9ac197dadb8edfffe747486649e02