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Cardiovascular Risk in Psoriasis: Current State of the Art

Authors :
Roberto Bitto
Matteo Casale
Salvatore Santo Signorelli
Giuseppe Dattilo
Claudio Guarneri
Francesco Borgia
Niki Katsiki
Claudia Morabito
Serafinello P Cannavò
Source :
Current Vascular Pharmacology. 17:85-91
Publication Year :
2018
Publisher :
Bentham Science Publishers Ltd., 2018.

Abstract

Psoriasis (Pso) is a chronic inflammatory immune-mediated skin disease associated with several comorbidities. Despite the growing number of studies providing evidence for the link between Pso and Cardiovascular (CV) disorders, there are still many unsolved questions, dealing with the role of the skin disease as an independent risk factor for CV events, the influence of Pso severity and duration on CV damage, the presence of Psoriatic Arthritis (PsA) as a predictor of increased CV mortality and morbidity and the detection of reliable clinical, laboratory and/or instrumental parameters to stratify CV risk in psoriatic patients. Moreover, it remains to clarify if the early treatment of the dermatosis may lower CV risk. In this paper we will try to provide answers to these queries in the light of the updated data of the literature.

Details

ISSN :
15701611
Volume :
17
Database :
OpenAIRE
Journal :
Current Vascular Pharmacology
Accession number :
edsair.doi.dedup.....d649fecf05f3e389c3dfd38c02220a8d