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Effects of physical training on endothelial function and limb blood flow in type 2 diabetes
- Source :
- Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. 32(5)
- Publication Year :
- 2007
-
Abstract
- The term “endothelial dysfunction” refers to the inability or attenuated effect of the endothelial cells in participating in the relaxation of the adjacent smooth muscle, thus causing less vasodilation. Although endothelial dysfunction is often seen in patients with type 2 diabetes, it does not necessarily follow that insulin resistance and (or) hyperglycemia is causing the inability to respond properly to vasodilatory stimuli. Rather, this could be related to the impact of concomitant cardiovascular risk factors that are almost invariably present in patients with type 2 diabetes. The impact of physical training — or the opposite, inactivity — on endothelial function is not fully elucidated. Some studies have shown positive effects of physical training, whereas others have not. In general, physical training can improve endothelial function when this is impaired. However, physical training does not seem to have any effect on endothelial function when this is normal.
- Subjects :
- medicine.medical_specialty
Physiology
Endocrinology, Diabetes and Metabolism
medicine.medical_treatment
Type 2 diabetes
Insulin resistance
Smooth muscle
Physiology (medical)
Internal medicine
medicine
Humans
Endothelial dysfunction
Exercise
Leg
Nutrition and Dietetics
Relaxation (psychology)
business.industry
Insulin
General Medicine
Blood flow
medicine.disease
Vasodilation
Diabetes Mellitus, Type 2
Cardiology
Endothelium, Vascular
business
Function (biology)
Subjects
Details
- ISSN :
- 17155312
- Volume :
- 32
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme
- Accession number :
- edsair.doi.dedup.....d681d321a00af6f20ade5ed6c9606860