Different Splenic Uptake of Tc-99m Sulfur Colloid and Tc-99m Heat-Denatured Red Blood Cells in an Infant With Complete Situs Inversus

A 5-week-old male infant with complete situs inversus and suspected asplenia underwent Tc-99m sulfur colloid and Tc-99m heat-denatured red blood cell (RBC) imaging to evaluate possible spleen function. The heat-denatured Tc-99m-labeled RBC scan revealed intense uptake in the normal-shaped right-side spleen, whereas the Tc-99m sulfur colloid scan showed only slight uptake in the reticuloendothelial system (RES). Therefore, the patient received antipneumococcal vaccination and antibiotic prophylaxis to prevent infections in the future.