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Renal and bone marrow cells fuse after renal ischemic injury
- Source :
- Journal of the American Society of Nephrology : JASN. 18(12)
- Publication Year :
- 2007
-
Abstract
- After acute kidney injury, bone marrow cells contribute to renal repair by converting into renal cells, but the mechanism of this conversion is not well understood. To determine whether cell fusion between bone marrow cells and injured renal cells plays a role, we subjected female mice expressing
- Subjects :
- Nephrology
Male
medicine.medical_specialty
Pathology
Urinary system
Bone Marrow Cells
Mice, Transgenic
Biology
urologic and male genital diseases
Kidney
Sensitivity and Specificity
Mice
Sex Factors
Ischemia
Internal medicine
medicine
Animals
In Situ Hybridization, Fluorescence
Bone Marrow Transplantation
Recombination, Genetic
Cell fusion
Microscopy, Confocal
Acute kidney injury
Ischemic injury
General Medicine
medicine.disease
Coculture Techniques
medicine.anatomical_structure
Female
Bone marrow
Subjects
Details
- ISSN :
- 15333450
- Volume :
- 18
- Issue :
- 12
- Database :
- OpenAIRE
- Journal :
- Journal of the American Society of Nephrology : JASN
- Accession number :
- edsair.doi.dedup.....d7626854be903d84b73ac107996e93b4