A comparative study of the five-repetition sit-to-stand test and the 30-second sit-to-stand test to assess exercise tolerance in COPD patients

Qin Zhang,1 Yan-xia Li,2 Xue-lian Li,3 Yan Yin,1 Rui-lan Li,1 Xin Qiao,1 Wei Li,1 Hai-feng Ma,1 Wen-hui Ma,1 Yu-feng Han,1 Guang-qiao Zeng,4 Qiu-yue Wang,1 Jian Kang,1 Gang Hou1 1Institute of Respiratory Disease, First Hospital of China Medical University, Shenyang, China; 2Department of Respiratory Medicine, First Hospital of Dalian Medical University, Dalian, China; 3Department of Epidemiology, School of Public Health, China Medical University, Shenyang, China; 4State Key Laboratory of Respiratory Disease, National Clinical Research Center of Respiratory Disease, Guangzhou Institute of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China Purpose: The sit-to-stand test (STST) has been used to evaluate the exercise tolerance of patients with COPD. However, mutual comparisons to predict poor exercise tolerance have been hindered by the variety of STST modes used in previous studies, which also did not consider patients’ subjective perceptions of different STST modes. Our aim was to compare the five-repetition sit-to-stand test (5STS) with the 30-second sit-to-stand test (30STS) for predicting poor performance in the six-minute walking test and to evaluate patients’ subjective perceptions to determine the optimal mode for clinical practice. Patients and methods: Patients with stable COPD performed 5STS, 30STS and the 6MWT and then evaluated their feelings about the two STST modes by Borg dyspnea score and a questionnaire. Moreover, we collected data through the pulmonary function test, mMRC dyspnea score, COPD assessment test and quadriceps muscle strength (QMS). A receiver operating characteristic curve analysis of the 5STS and 30STS results was used to predict 6-minute walk distance (6MWD)