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Figure S4 from JQ1 Induces DNA Damage and Apoptosis, and Inhibits Tumor Growth in a Patient-Derived Xenograft Model of Cholangiocarcinoma

Authors :
Karina J. Yoon
Eddy S. Yang
James E. Bradner
Robert C.A.M. van Waardenburg
Xiangqin Cui
Joseph H. Richardson
Sushanth Reddy
Marty J. Heslin
J. Pablo Arnoletti
John D. Christein
Leona N. Council
Tracy L. Gamblin
Aubrey L. Miller
Patrick L. Garcia
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Immunoblot analysis showing that JQ1 downregulates TEK, Chk1, MSH2 and LCK expression in CCA2 tumors, but not in CCA1 tumors.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....d7a452940d6358b754c0626b806e616c
Full Text :
https://doi.org/10.1158/1535-7163.22505407