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Childhood alopecia areata-Data from the National Alopecia Areata Registry
- Source :
- Pediatric Dermatology. 35:164-169
- Publication Year :
- 2018
- Publisher :
- Wiley, 2018.
-
Abstract
- Background/objectives Alopecia areata may occur at any age and is the third-most-common dermatosis in children. The objective of this study was to investigate the clinical and epidemiologic features of children and adolescents with alopecia areata based on the data of the National Alopecia Areata registry on children and adolescents. Methods Two thousand two hundred eighteen children and adolescents with alopecia areata self-enrolled in the National Alopecia Areata Registry and completed a web-based, self-administered, short-intake screening questionnaire (first tier). In the second tier, 643 patients participated in a clinical examination and completed a long-form questionnaire. Results Mean age of onset was 5.9 ± 4.1 years. With a female to male ratio of 1.5:1, alopecia areata was more prevalent in girls, but boys were significantly more likely to have a severe type (P = .009). One-fourth of all children had a positive family history, with 8% having more than three affected relatives. The disease most commonly associated with alopecia areata was atopic dermatitis (32.7%). Conclusion Childhood alopecia areata is more prevalent in girls than in boys, but boys have more extensive alopecia areata. Despite the low prevalence, congenital alopecia areata is an important differential diagnosis for neonatal hair loss. Alopecia areata runs in families, suggesting an underlying genetic background. One-quarter of the children reported at least one affected first-degree relative; 8% had more than three affected relatives.
- Subjects :
- Male
medicine.medical_specialty
Adolescent
Alopecia Areata
Physical examination
Comorbidity
Dermatology
Disease
030207 dermatology & venereal diseases
03 medical and health sciences
0302 clinical medicine
Surveys and Questionnaires
Prevalence
medicine
Humans
Registries
Family history
Child
skin and connective tissue diseases
integumentary system
medicine.diagnostic_test
business.industry
Atopic dermatitis
Alopecia areata
medicine.disease
United States
body regions
Child, Preschool
030220 oncology & carcinogenesis
Hair Disorder
Pediatrics, Perinatology and Child Health
Female
Differential diagnosis
business
Congenital Alopecia
Subjects
Details
- ISSN :
- 07368046
- Volume :
- 35
- Database :
- OpenAIRE
- Journal :
- Pediatric Dermatology
- Accession number :
- edsair.doi.dedup.....d7c3f5205b8fcdc5446bcac0522b2055