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Phytotherapy in Inflammatory Lung Diseases: An Emerging Therapeutic Interventional Approach

Authors :
Philip M. Hansbro
Pawan Kumar Maurya
Nicole G. Hansbro
Dinesh Kumar Chellappan
Ridhima Wadhwa
Kylie A. Williams
Shakti D. Shukla
Kamal Dua
Gaurav Gupta
Trudi Collet
Brian G. Oliver
Source :
Phytochemistry: An in-silico and in-vitro Update ISBN: 9789811369193
Publication Year :
2019
Publisher :
Springer, 2019.

Abstract

Chronic obstructive pulmonary disease (COPD) and asthma are the most common inflammatory respiratory diseases related to an increase in mortality and morbidity. Generally, bronchodilators, s- agonists, anticholinergics and theophylline used for treatment in these conditions and administered by inhalation for delivery, have localized and systematic effects. The adverse effects are due to pharmacodynamic and pharmacokinetic changes and especially drug-drug and drug-disease interactions. However, phytotherapy is classical and widespread throughout the world for the treatment of ailments. This chapter highlights cellular and molecular mediators involved in COPD and asthma, the shortcomings of current therapies and the emerging need of phytomedicines. Phytomedicine supports respiratory physiology, bronchial action and possesses antioxidants to maintain homeostasis.

Details

Database :
OpenAIRE
Journal :
Phytochemistry: An in-silico and in-vitro Update ISBN: 9789811369193
Accession number :
edsair.doi.dedup.....d7ebb1c84a4ccea8c74109bd346be1ec