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Assessment of hepatocellular carcinoma vascularity before and after transcatheter arterial chemoembolization by using first pass perfusion weighted MR imaging
- Source :
- World Journal of Gastroenterology. 10:1152
- Publication Year :
- 2004
- Publisher :
- Baishideng Publishing Group Inc., 2004.
-
Abstract
- To assess the vascularity of hepatocellular carcinoma (HCC) before and after transcatheter arterial chemoembolization (TACE) with the quantitative parameters obtained by first pass perfusion weighted MR imaging (FP-MRI).Seventeen consecutive patients with one to three lesions in liver underwent FP-MRI before treatment. FP-MRI was also performed one, three, six, nine months, and one year after TACE. The baseline signal intensity (S0) of pre-TACE and one month after TACE was analyzed, the vascularity of HCC assessed by steepest slope of the signal intensity versus time curves (SS) was blindly correlated with their DSA feature and clinical outcome.No significant difference was found on baseline signal intensity (S0) between pre-TACE and one month after TACE (F=0.309, P=0.583), The SS (mean, 32% per second) of lesion one month after TACE was lower than that of pre-TACE (mean, 69% per second), but with no statistical significance (F=3.067, P=0.092). When local recurrence occurred, the time intensity curves became steeper. The vascularity of HCC before and after TACE graded by SS closely correlated with that by DSA (K=0.453, P0.05).FP-MRI is a useful criterion for selecting effective interventional treatment for patients with HCC in their initial treatment and during follow up.
- Subjects :
- Adult
Male
Liver Cancer
medicine.medical_specialty
Carcinoma, Hepatocellular
Magnetic resonance angiography
Lesion
Vascularity
Text mining
Statistical significance
medicine
Humans
Chemoembolization, Therapeutic
Transcatheter arterial chemoembolization
Aged
Neovascularization, Pathologic
medicine.diagnostic_test
business.industry
Microcirculation
Liver Neoplasms
Gastroenterology
General Medicine
Middle Aged
medicine.disease
Mr imaging
digestive system diseases
Hepatocellular carcinoma
Female
Radiology
medicine.symptom
business
Magnetic Resonance Angiography
Follow-Up Studies
Liver Circulation
Subjects
Details
- ISSN :
- 10079327
- Volume :
- 10
- Database :
- OpenAIRE
- Journal :
- World Journal of Gastroenterology
- Accession number :
- edsair.doi.dedup.....d8658ea5fb71fee7d1eab02be1bdc1dd