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Acetylcholinesterase inhibition starting from extracts of Bauhinia variegata L., Bauhinia var. candida (Aiton) Buch.-Ham., and Bauhinia ungulata L

Authors :
Kamilla Monteiro dos Santos
Guilherme Araújo Lacerda
Priscila Sant'Ana Gonçalves
Maria José Nunes de Paiva
Source :
Revista da Sociedade Brasileira de Medicina Tropical, Vol 44, Iss 6, Pp 781-783 (2011), Revista da Sociedade Brasileira de Medicina Tropical v.44 n.6 2011, Revista da Sociedade Brasileira de Medicina Tropical, Sociedade Brasileira de Medicina Tropical (SBMT), instacron:SBMT
Publication Year :
2011
Publisher :
Sociedade Brasileira de Medicina Tropical (SBMT), 2011.

Abstract

INTRODUCTION: A treatment to the Alzheimer's disease consists inhibition of the acetylcholinesterase, which is responsible for the acetylcholine control in the synapses. METHODS: We have investigated the potential of inhibition of the acetylcholinesterase produced by hexane extracts of leaves, branches, and flowers from three Bauhinia specimens, which is based on the technique of thin layer chromatography and on identifying the organ of the plant that possesses larger concentration of inhibitors. RESULTS: Retention factor analysis shows values of 0.31aA, 0.31aA, and 0.46aB for flowers B. variegata, B. var. candida, and B. ungulata, respectively. CONCLUSIONS: The flower extract of B. ungulata is the most suitable for further studies on this inhibition.

Details

Language :
English
ISSN :
16789849
Volume :
44
Issue :
6
Database :
OpenAIRE
Journal :
Revista da Sociedade Brasileira de Medicina Tropical
Accession number :
edsair.doi.dedup.....d86cbd8c05ab97eb80dd021e3257cf08