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Acetylcholinesterase inhibition starting from extracts of Bauhinia variegata L., Bauhinia var. candida (Aiton) Buch.-Ham., and Bauhinia ungulata L
- Source :
- Revista da Sociedade Brasileira de Medicina Tropical, Vol 44, Iss 6, Pp 781-783 (2011), Revista da Sociedade Brasileira de Medicina Tropical v.44 n.6 2011, Revista da Sociedade Brasileira de Medicina Tropical, Sociedade Brasileira de Medicina Tropical (SBMT), instacron:SBMT
- Publication Year :
- 2011
- Publisher :
- Sociedade Brasileira de Medicina Tropical (SBMT), 2011.
-
Abstract
- INTRODUCTION: A treatment to the Alzheimer's disease consists inhibition of the acetylcholinesterase, which is responsible for the acetylcholine control in the synapses. METHODS: We have investigated the potential of inhibition of the acetylcholinesterase produced by hexane extracts of leaves, branches, and flowers from three Bauhinia specimens, which is based on the technique of thin layer chromatography and on identifying the organ of the plant that possesses larger concentration of inhibitors. RESULTS: Retention factor analysis shows values of 0.31aA, 0.31aA, and 0.46aB for flowers B. variegata, B. var. candida, and B. ungulata, respectively. CONCLUSIONS: The flower extract of B. ungulata is the most suitable for further studies on this inhibition.
- Subjects :
- Microbiology (medical)
lcsh:Arctic medicine. Tropical medicine
lcsh:RC955-962
Thin layer
Flowers
chemistry.chemical_compound
Botany
medicine
Cromatografia
Cholinesterase
Acetilcolinesterase
Chromatography
biology
Plant Stems
Bauhinia variegata
Bauhinia
Plant Extracts
food and beverages
biology.organism_classification
Acetylcholinesterase
Thin-layer chromatography
Bauhinia ungulata
Plant Leaves
Infectious Diseases
chemistry
biology.protein
Parasitology
Cholinesterase Inhibitors
Chromatography, Thin Layer
Acetylcholine
medicine.drug
Subjects
Details
- Language :
- English
- ISSN :
- 16789849
- Volume :
- 44
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Revista da Sociedade Brasileira de Medicina Tropical
- Accession number :
- edsair.doi.dedup.....d86cbd8c05ab97eb80dd021e3257cf08