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Short foveo-disc distance in situs inversus of optic disc
- Source :
- Scientific Reports, Scientific Reports, Vol 10, Iss 1, Pp 1-7 (2020)
- Publication Year :
- 2020
- Publisher :
- Nature Publishing Group UK, 2020.
-
Abstract
- Situs inversus of optic disc (SIOD) is thought to be a congenital optic disc abnormality that is caused by dysversion of optic nerve insertion. SIOD, however, has many additional features that cannot be explained by abnormal optic-nerve-insertion directionality. In this study, we measured the distance between the fovea and disc in 22 eyes of 15 SIOD patients. For comparison, two control eyes were matched with each SIOD eye by age and axial length. The vertical distance between the temporal vascular arcades also was measured. The foveo-disc distance was shorter in the SIOD eyes than in the control eyes, while the inter-arcade distance did not differ. Further, we measured the circumpapillary retinal nerve fiber layer thickness, which showed nasal crowding of two humps in the SIOD eyes. This nasal crowding disappeared when we shifted the circle scan by the mean difference (465 μm) of the foveal-disc distance between the two groups. Our findings suggest that the optic disc was located closer to the fovea than it would have been normally. Thus, SIOD might reflect incomplete expansion of the posterior pole in the direction of the fovea-disc axis.
- Subjects :
- 0301 basic medicine
Male
Retinal Ganglion Cells
Fovea Centralis
genetic structures
Posterior pole
Optic Disk
Nerve fiber layer
lcsh:Medicine
Developmental neurogenesis
Eye
Article
Retina
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Nerve Fibers
medicine
Humans
lcsh:Science
Aged
Multidisciplinary
business.industry
lcsh:R
Vertical distance
Retinal
Anatomy
Middle Aged
medicine.disease
Situs Inversus
eye diseases
Situs inversus
030104 developmental biology
medicine.anatomical_structure
chemistry
Regional Blood Flow
030221 ophthalmology & optometry
Optic nerve
lcsh:Q
Female
sense organs
Abnormality
Visual system
business
Optic disc
Subjects
Details
- Language :
- English
- ISSN :
- 20452322
- Volume :
- 10
- Database :
- OpenAIRE
- Journal :
- Scientific Reports
- Accession number :
- edsair.doi.dedup.....d89eab40446ab512609cf94b4a295582