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Early Rhythm-Control Therapy in Patients with Atrial Fibrillation

Authors :: Paulus, Kirchhof
A John, Camm
Andreas, Goette
Axel, Brandes
Lars, Eckardt
Arif, Elvan
Thomas, Fetsch
Isabelle C, van Gelder
Doreen, Haase
Laurent M, Haegeli
Frank, Hamann
Hein, Heidbüchel
Gerhard, Hindricks
Josef, Kautzner
Karl-Heinz, Kuck
Lluis, Mont
G Andre, Ng
Jerzy, Rekosz
Norbert, Schoen
Ulrich, Schotten
Anna, Suling
Jens, Taggeselle
Sakis, Themistoclakis
Eik, Vettorazzi
Panos, Vardas
Karl, Wegscheider
Stephan, Willems
Harry J G M, Crijns
Günter, Breithardt
Anna-Maria, Wnuk-Wojnar
Cardiovascular Centre (CVC)
RS: Carim - H08 Experimental atrial fibrillation
Fysiologie
Cardiologie
MUMC+: MA Cardiologie (9)
RS: Carim - H01 Clinical atrial fibrillation
EAST-AFNET 4 Trial Investigators
Source :: Kirchhof, P, Camm, A J, Goette, A, Brandes, A, Eckardt, L, Elvan, A, Fetsch, T, van Gelder, I C, Haase, D, Haegeli, L M, Hamann, F, Heidüchel, H, Hindricks, G, Kautzner, J, Kuck, K-H, Mont, L, Ng, G A, Rekosz, J, Schoen, N, Schotten, U, Suling, A, Taggeselle, J, Themistoclakis, S, Vettorazzi, E, Vardas, P, Wegscheider, K, Willems, S, Crijns, H J G M, Breithardt, G & EAST-AFNET 4 Trial Investigators 2020, ' Early Rhythm-Control Therapy in Patients with Atrial Fibrillation ', The New England Journal of Medicine, vol. 383, no. 14, pp. 1305-1316 . https://doi.org/10.1056/NEJMoa2019422, New England Journal of Medicine, 383(14), 1305-1316. MASSACHUSETTS MEDICAL SOC, New England Journal of Medicine, 383(14), 1305-1316. MASSACHUSETTS MEDICAL SOCIETY, The New England journal of medicine
Publication Year :: 2020
Abstract: BackgroundDespite improvements in the management of atrial fibrillation, patients with this condition remain at increased risk for cardiovascular complications. It is unclear whether early rhythm-control therapy can reduce this risk. MethodsIn this international, investigator-initiated, parallel-group, open, blinded-outcome-assessment trial, we randomly assigned patients who had early atrial fibrillation (diagnosed