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Imaging Sequences for Hyperpolarized Solids
- Source :
- Molecules, Molecules, Vol 26, Iss 133, p 133 (2021), Molecules (Basel, Switzerland), vol 26, iss 1, Volume 26, Issue 1
- Publication Year :
- 2020
- Publisher :
- MDPI AG, 2020.
-
Abstract
- Hyperpolarization is one of the approaches to enhance Nuclear Magnetic Resonance (NMR) and Magnetic Resonance Imaging (MRI) signal by increasing the population difference between the nuclear spin states. Imaging hyperpolarized solids opens up extensive possibilities, yet is challenging to perform. The highly populated state is normally not replenishable to the initial polarization level by spin-lattice relaxation, which regular MRI sequences rely on. This makes it necessary to carefully &ldquo<br />budget&rdquo<br />the polarization to optimize the image quality. In this paper, we present a theoretical framework to address such challenge under the assumption of either variable flip angles or a constant flip angle. In addition, we analyze the gradient arrangement to perform fast imaging to overcome intrinsic short decoherence in solids. Hyperpolarized diamonds imaging is demonstrated as a prototypical platform to test the theory.
- Subjects :
- Magnetic Resonance Spectroscopy
Image quality
Image Processing
Physics::Medical Physics
Pharmaceutical Science
02 engineering and technology
Signal-To-Noise Ratio
01 natural sciences
Phantoms
Imaging
Analytical Chemistry
Computer-Assisted
Theoretical and Computational Chemistry
Drug Discovery
Image Processing, Computer-Assisted
magnetic resonance imaging
Hyperpolarization (physics)
hyperpolarization
Physics
Carbon Isotopes
education.field_of_study
Fourier Analysis
medicine.diagnostic_test
Phantoms, Imaging
Equipment Design
021001 nanoscience & nanotechnology
Polarization (waves)
Magnetic Resonance Imaging
Chemistry (miscellaneous)
Calibration
Biomedical Imaging
Molecular Medicine
0210 nano-technology
Algorithms
Quantum decoherence
Population
Article
lcsh:QD241-441
Medicinal and Biomolecular Chemistry
Magnetics
lcsh:Organic chemistry
Flip angle
0103 physical sciences
medicine
Physical and Theoretical Chemistry
010306 general physics
education
Organic Chemistry
Magnetic resonance imaging
Computational physics
flip angle
Diamond
Subjects
Details
- ISSN :
- 14203049
- Volume :
- 26
- Database :
- OpenAIRE
- Journal :
- Molecules
- Accession number :
- edsair.doi.dedup.....d90137a39a1ab0f476f3693b56511db7