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Supplementation with Beef Extract Improves Exercise Performance and Reduces Post-Exercise Fatigue Independent of Gut Microbiota
- Source :
- Nutrients, Nutrients, Vol 10, Iss 11, p 1740 (2018), Volume 10, Issue 11
- Publication Year :
- 2018
- Publisher :
- MDPI, 2018.
-
Abstract
- Beef extract (BE) is a nutritional supplement obtained by cooking beef meat. Compared with traditional chicken essence or clam extract, BE is cheaper to produce and may be used for wound healing, as a chemotherapy supplement, or to prevent fatigue. In this study, we evaluated the potential beneficial effects of BE on exercise performance and the related role of the gut microbiota. Pathogen-free male BALB/c mice were divided into three groups to receive vehicle or BE (0, 12.3, or 24.6 mL/kg) by oral gavage for 28 days. Exercise performance was evaluated using forelimb grip strength, swimming time to exhaustion, and physiological levels of fatigue-related biomarkers (serum lactate, blood urea nitrogen, and glucose levels) after physical challenges. BE supplementation elevated endurance and grip strength in a dose-dependent manner<br />significantly decreased lactate and blood urea nitrogen levels after physical challenge<br />and significantly increased muscle glycogen content. The germ-free mice supplemented with BE or an equal-calorie portion of albumin did not show significant differences from the other groups in exercise performance and levels of related biomarkers. Therefore, BE supplementation improved endurance and reduced fatigue, which might be related to BE composition, but had no correlation with the gut microbiota.
- Subjects :
- 0301 basic medicine
Male
Physiology
lcsh:TX341-641
exercise performance
Gut flora
Article
Blood Urea Nitrogen
03 medical and health sciences
Grip strength
chemistry.chemical_compound
0302 clinical medicine
Increased muscle glycogen content
Physical Conditioning, Animal
Exercise performance
Medicine
Animals
Cooking
Lactic Acid
Muscle Strength
swimming
Muscle, Skeletal
Blood urea nitrogen
Fatigue
Mice, Inbred BALB C
030109 nutrition & dietetics
Nutrition and Dietetics
biology
Glycogen
antifatigue
Hand Strength
business.industry
Albumin
030229 sport sciences
beef extract
biology.organism_classification
Gastrointestinal Microbiome
Red Meat
chemistry
glycogen
Dietary Supplements
Physical Endurance
Cattle
business
Wound healing
lcsh:Nutrition. Foods and food supply
Food Science
Subjects
Details
- Language :
- English
- ISSN :
- 20726643
- Volume :
- 10
- Issue :
- 11
- Database :
- OpenAIRE
- Journal :
- Nutrients
- Accession number :
- edsair.doi.dedup.....d97eb610b2399f1fe5d08a9871578171