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The choice for invasive prenatal tests after subfertility
- Source :
- Human Fertility, 23(2), 134-141. Informa Healthcare
- Publication Year :
- 2020
-
Abstract
- The aim of this study was to test whether women who conceived after a period of subfertility are less likely to undergo invasive prenatal testing (IPT) and determine factors of influence in that decision. We conducted a retrospective study at the Maastricht University Medical Centre (MUMC+) to compare the rates of IPT following abnormal results of combined first trimester screening (cFTS) or second trimester screening (STS), or because of advanced maternal age among women tested for the effect of type and duration of subfertility and history of fertility investigations and/or treatment. We included 977 women who underwent IPT between January 2010 and December 2013. The women who conceived after fertility investigations and/or treatment had lower rates of IPT following abnormal STS (12.6% vs. 20.0%, OR = 0.58, 95% CI; 0.34-0.97). The difference was not statistically significant after correction for maternal age and severity of the foetal anomaly. Maternal age was, in contrast to fertility treatment or duration of subfertility, related to the choice of IPT among formerly subfertile women. Therefore, the lower uptake of IPT in women conceiving after a period of subfertility is dependent on the indication for IPT and maternal age and less on the type and duration of subfertility.
- Subjects :
- Adult
medicine.medical_specialty
Down syndrome
Reproductive Techniques, Assisted
subfertility
03 medical and health sciences
0302 clinical medicine
SOFT MARKERS
Prenatal Diagnosis
TERMINATION
parasitic diseases
medicine
Odds Ratio
Humans
ADVANCED MATERNAL AGE
Foetal anomaly
AMNIOCENTESIS
030212 general & internal medicine
Advanced maternal age
DOWN-SYNDROME
FETAL
foetal anomaly
Pregnancy
Fetus
030219 obstetrics & reproductive medicine
Invasive prenatal testing
medicine.diagnostic_test
business.industry
Obstetrics
assisted reproduction
Obstetrics and Gynecology
WOMEN
General Medicine
medicine.disease
PREVALENCE
Prenatal screening
PREGNANCY
Reproductive Medicine
prenatal screening
SCREENING-PROGRAM
Amniocentesis
Female
business
Subjects
Details
- Language :
- English
- ISSN :
- 14647273
- Database :
- OpenAIRE
- Journal :
- Human Fertility, 23(2), 134-141. Informa Healthcare
- Accession number :
- edsair.doi.dedup.....d9ad4419874ff83c5518d8da695acda4