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A dominant insulin-specific and islet-destructive T-cell response is sufficient to activate CD8 T cells directed against the fatty-acid receptor GPR40
- Source :
- Cellular and Molecular Immunology
- Publication Year :
- 2019
- Publisher :
- Springer Science and Business Media LLC, 2019.
- Subjects :
- T-Lymphocytes
medicine.medical_treatment
Adaptive immunity
Immunology
Autoimmunity
CD8-Positive T-Lymphocytes
Lymphocyte Activation
T cell response
Autoantigens
Receptors, G-Protein-Coupled
Islets of Langerhans
Text mining
Free fatty acid receptor 1
Correspondence
medicine
Animals
Insulin
Immunology and Allergy
Cytotoxic T cell
Amino Acid Sequence
Receptor
chemistry.chemical_classification
geography
geography.geographical_feature_category
business.industry
Fatty Acids
Fatty acid
Islet
Cell biology
Mice, Inbred C57BL
Mechanisms of disease
Infectious Diseases
chemistry
business
Subjects
Details
- ISSN :
- 20420226 and 16727681
- Volume :
- 17
- Database :
- OpenAIRE
- Journal :
- Cellular & Molecular Immunology
- Accession number :
- edsair.doi.dedup.....d9c118bc8971bce7fc12fb537f81d02d
- Full Text :
- https://doi.org/10.1038/s41423-019-0309-y