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Bridging the Gap in Personalized Oncology using Omics Data and Epidemiology

Authors :
Dina El Harouni
Farah Nabil
Hassan Adwan
Source :
Zaguán. Repositorio Digital de la Universidad de Zaragoza, instname
Publication Year :
2018

Abstract

As Personalized Medicine tailored the field of precision oncology, many challenges have been arising to fulfill the dream of a full personalized health integrated system in cancer therapy. Personalized oncology has been addressed through the past decades in multiple disease and various stages using high throughput technology. This review gives hand on recent advances of personalized oncology in several cancer disease models including leukemia, melanoma, breast cancer, lung cancer, colorectal cancer, and prostate cancer. Moreover, the review enumerates technology-based assessment of personalized biomarkers, including chip micro-array, organ on chip, and next generation sequencing. Meanwhile addressing challenges faced in implementing true personalized health cancer in oncology setting, this review focuses on bridging the gap between omics data analytics and epidemiology to overcome the true challenge of direct application.

Details

Database :
OpenAIRE
Journal :
Zaguán. Repositorio Digital de la Universidad de Zaragoza, instname
Accession number :
edsair.doi.dedup.....d9e1942ff1e0bb6853d51afb377b968a