The Vanishing Adrenal Glands: A Transient Regression of Adrenal Lymphoma After a Single Dose of 1 mg Dexamethasone

Authors :: Emma Hatfield
Hessa Boharoon
Shamaila Zaman
Sasha Marks
Ali Alsafi
Karim Meeran
Neelam Khalid
Neil E. Hill
Rashpal Flora
Source :: AACE Clinical Case Reports, AACE Clinical Case Reports, Vol 7, Iss 2, Pp 109-112 (2021)
Publication Year :: 2021
Publisher :: Elsevier BV, 2021.
Abstract: Objective: Dexamethasone is a known treatment for lymphoma, but the potency and rapidity of its effect have not been recognized. We present a case of bilateral adrenal lymphoma that significantly reduced in size after a single dose of dexamethasone. Methods: We present the clinical course and investigations, including adrenocorticotropic hormone, cortisol, short synacthen test, computed tomography (CT), and adrenal biopsy results. Results: A 52-year-old man had a fall and was incidentally found to have bilateral adrenal masses (left, 6 cm; right, 5 cm) on CT. His adrenal function tests included plasma metanephrines (normetanephrine, 830 pmol/L [normal

Subjects :: medicine.medical_specialty
Urology
Case Report
030209 endocrinology & metabolism
Adrenocorticotropic hormone
Normetanephrine
Diseases of the endocrine glands. Clinical endocrinology
PET, positron emission tomography
Primary Adrenal Insufficiency
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Biopsy
Adrenal insufficiency
Medicine
PAI, primary adrenal insufficiency
adrenal cancer
Dexamethasone
medicine.diagnostic_test
business.industry
General Medicine
Metanephrines
RC648-665
medicine.disease
CT, computed tomography
ONDST, overnight dexamethasone suppression test
adrenal
chemistry
030220 oncology & carcinogenesis
ACTH, adrenocorticotropic hormone
SST, short synacthen test
adrenal insufficiency
business
13 Education
DLBCL, diffuse large B-cell lymphoma
Diffuse large B-cell lymphoma
medicine.drug

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