Back to Search
Start Over
Impact of Body Mass Index on the Survival of Patients with Sepsis with Different Modified NUTRIC Scores
- Source :
- Nutrients, Nutrients, Vol 13, Iss 1873, p 1873 (2021), Volume 13, Issue 6
- Publication Year :
- 2021
- Publisher :
- MDPI, 2021.
-
Abstract
- Nutritional status affects the survival of patients with sepsis. This retrospective study analyzed the impact of body mass index (BMI) and modified nutrition risk in critically ill (mNUTRIC) scores on survival of these patients. Data of 1291 patients with sepsis admitted to the intensive care unit (ICU) were extracted. The outcomes were mortality, duration of stay, ICU stay, and survival curve for 90-day mortality. Logistic regression analysis was performed to examine the risk factors for mortality. Cytokine and biomarker levels were analyzed in 165 patients. The 90-day survival of underweight patients with low mNUTRIC scores was significantly better than that of normal-weight patients with low mNUTRIC scores (70.8% vs. 58.3%, respectively<br />p = 0.048). Regression model analysis revealed that underweight patients with low mNUTRIC scores had a lower risk of mortality (odds ratio = 0.557<br />p = 0.082). Moreover, normal-weight patients with low mNUTRIC scores had the lowest human leukocyte antigen DR (HLA-DR) level on days 1 (underweight vs. normal weight vs. overweight: 94.3 vs. 82.1 vs. 94.3, respectively<br />p = 0.007) and 3 (91.8 vs. 91.0 vs. 93.2, respectively<br />p = 0.047). Thus, being underweight may not always be harmful if patients have optimal clinical nutritional status. Additionally, HLA-DR levels were the lowest in patients with low survival.
- Subjects :
- Male
medicine.medical_specialty
Taiwan
Nutritional Status
Comorbidity
Overweight
Logistic regression
Lower risk
survival
Article
law.invention
Body Mass Index
sepsis
03 medical and health sciences
0302 clinical medicine
underweight
law
Risk Factors
Internal medicine
medicine
Humans
TX341-641
030212 general & internal medicine
Survival analysis
Aged
Retrospective Studies
Nutrition and Dietetics
business.industry
Nutrition. Foods and food supply
Malnutrition
030208 emergency & critical care medicine
Odds ratio
Length of Stay
Middle Aged
Intensive care unit
Survival Analysis
nutrition
Female
Underweight
medicine.symptom
business
Body mass index
Food Science
Subjects
Details
- Language :
- English
- ISSN :
- 20726643
- Volume :
- 13
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Nutrients
- Accession number :
- edsair.doi.dedup.....da24a3a4aef915f35e52be47c8feb41f