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Automated electrocardiographic quantification of myocardial scar in patients undergoing primary prevention implantable cardioverter-defibrillator implantation: Association with mortality and subsequent appropriate and inappropriate therapies
- Source :
- Heart Rhythm. 17:1664-1671
- Publication Year :
- 2020
- Publisher :
- Elsevier BV, 2020.
-
Abstract
- Myocardial scarring from infarction or nonischemic fibrosis forms an arrhythmogenic substrate. The Selvester QRS score has been developed to estimate myocardial scar from the 12-lead electrocardiogram.; We aimed to assess the value of an automated version of the Selvester QRS score for the prediction of implantable cardioverter-defibrillator (ICD) therapy and death in patients undergoing primary prevention ICD implantation.; Unselected patients undergoing primary prevention ICD implantation were included in this retrospective, observational, multicenter study. The QRS score was calculated automatically from a digital standard preimplantation 12-lead electrocardiogram and was correlated to the occurrence of death and appropriate and inappropriate shocks during follow-up. Analyses were performed in groups defined by QRS duration < 130 ms vs ≥ 130 ms.; Overall, 1047 patients (872 [83%] men; median age 64 years IQR [55-71]) with ischemic (648, 62%) or nonischemic (399, 38%) cardiomyopathy were included. The median QRS duration was 123 ms (interquartile range [IQR] 111-157 ms), and the median QRS score was 5 (IQR 2-8). The QRS duration was
- Subjects :
- Male
medicine.medical_specialty
medicine.medical_treatment
Infarction
030204 cardiovascular system & hematology
Risk Assessment
Sudden cardiac death
Cicatrix
Electrocardiography
03 medical and health sciences
QRS complex
0302 clinical medicine
Risk Factors
Interquartile range
Median QRS Duration
Physiology (medical)
Internal medicine
Myocardial scarring
medicine
Humans
cardiovascular diseases
030212 general & internal medicine
Aged
Retrospective Studies
Heart Failure
business.industry
Incidence
Myocardium
Middle Aged
medicine.disease
Implantable cardioverter-defibrillator
Defibrillators, Implantable
3. Good health
Europe
Primary Prevention
Survival Rate
Death, Sudden, Cardiac
Heart failure
cardiovascular system
Cardiology
Female
medicine.symptom
Cardiology and Cardiovascular Medicine
business
circulatory and respiratory physiology
Subjects
Details
- ISSN :
- 15475271
- Volume :
- 17
- Database :
- OpenAIRE
- Journal :
- Heart Rhythm
- Accession number :
- edsair.doi.dedup.....da28f7e491f89fd98104d900b68796d0