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Cytological diagnosis of pediatric thyroid nodule in perspective of the Bethesda System for Reporting Thyroid Cytopathology
- Source :
- Journal of Cytology, Vol 33, Iss 4, Pp 220-223 (2016), Journal of Cytology
- Publication Year :
- 2016
- Publisher :
- Medknow, 2016.
-
Abstract
- Background: Thyroid nodule is one of the most common endocrinopathies occurring children and adolescents. Though thyroid nodule is rare in the pediatric age group, the rate of malignancy is much higher in this age group compared to adult population. Aim: The objective is to study the application of The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) in pediatric patients and compare the findings with histology. Materials and Methods: A total of 218 cases younger than 18 years were studied in a 4-year period from August 2010 to July 2014. The smears were categorized according to TBSRTC into six categories — Nondiagnostic, benign, atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS), suspicious for follicular neoplasm (SFN), suspicious for malignancy (SM), and malignancy. Results: Out of 218 cases, 33 were males and 185 were females. Histological follow-up was available in 44 cases. The diagnosis according to TBSRTC included 12 (5.5%) nondiagnostic, 151 (69.26%) benign, 23 (10.5%) AUS/FLUS, 18 (8.2%) SFN, 5 (2.3%) SM, and 9 (4.1%) malignancy cases. On histological follow-up, the rate of malignancy in each category was 0%, 0%, 8.3%, 10% 100%, and 100%, respectively. Conclusion: The study demonstrates that TBSRTC in pediatric thyroid nodule is as sensitive and specific as in adults, especially with 100% accuracy in the diagnosis of benign and malignant categories.
- Subjects :
- medicine.medical_specialty
Histology
Cytopathology
the Bethesda System
thyroid nodule
030209 endocrinology & metabolism
Malignancy
Pathology and Forensic Medicine
03 medical and health sciences
0302 clinical medicine
medicine
Atypia
lcsh:QH573-671
Gynecology
Suspicious for Malignancy
lcsh:Cytology
business.industry
Thyroid
Nodule (medicine)
medicine.disease
Dermatology
Bethesda system for reporting thyroid cytopathology
medicine.anatomical_structure
030220 oncology & carcinogenesis
Original Article
medicine.symptom
business
Subjects
Details
- ISSN :
- 09709371
- Volume :
- 33
- Database :
- OpenAIRE
- Journal :
- Journal of Cytology
- Accession number :
- edsair.doi.dedup.....da7b85bd1c2c01c63001c43892bd84f9