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Immunomodulatory effects of phytogenics in chickens and pigs — A review
- Source :
- Asian-Australasian Journal of Animal Sciences, Vol 31, Iss 5, Pp 617-627 (2018), Asian-Australasian Journal of Animal Sciences
- Publication Year :
- 2018
- Publisher :
- Asian-Australasian Association of Animal Production Societies, 2018.
-
Abstract
- Environmental stressors like pathogens and toxins may depress the animal immune system through invasion of the gastrointestinal tract (GIT) tract, where they may impair performance and production, as well as lead to increased mortality rates. Therefore, protection of the GIT tract and improving animal health are top priorities in animal production. Being natural-sourced materials, phytochemicals are potential feed additives possessing multiple functions, including: anti-inflammatory, anti-fungal, anti-viral and antioxidative properties. This paper focuses on immunity-related physiological parameters regulated by phytochemicals, such as carvacrol, cinnamaldehyde, curcumin, and thymol; many studies have proven that these phytochemicals can improve animal performance and production. On the molecular level, the impact of inflammatory gene expression on underlying mechanisms was also examined, as were the effects of environmental stimuli and phytochemicals in initiating nuclear factor kappa B and mitogen-activated protein kinases signaling pathways and improving health conditions.
- Subjects :
- 0301 basic medicine
Phytogenics
Inflammatory Cytokines
Phytochemicals
lcsh:Animal biochemistry
Pharmacology
Biology
Proinflammatory cytokine
03 medical and health sciences
chemistry.chemical_compound
Immune system
Domestic Animals
Thymol
Immune Response
lcsh:QP501-801
lcsh:SF1-1100
Review Paper
Gastrointestinal tract
Kinase
0402 animal and dairy science
04 agricultural and veterinary sciences
040201 dairy & animal science
030104 developmental biology
chemistry
Curcumin
Animal Science and Zoology
lcsh:Animal culture
Signal transduction
Food Science
Subjects
Details
- Language :
- English
- ISSN :
- 19765517 and 10112367
- Volume :
- 31
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Asian-Australasian Journal of Animal Sciences
- Accession number :
- edsair.doi.dedup.....daad08a1aa916b7ec185a949928ed216