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Pseudo-Renal Tubular Acidosis: Conditions Mimicking Renal Tubular Acidosis

Authors :
Jerry Yee
Junior Uduman
Source :
Advances in Chronic Kidney Disease. 25:358-365
Publication Year :
2018
Publisher :
Elsevier BV, 2018.

Abstract

Hyperchloremic metabolic acidosis, particularly renal tubular acidosis, can pose diagnostic challenges. The laboratory phenotype of a low total carbon dioxide content, normal anion gap, and hyperchloremia may be misconstrued as hypobicarbonatemia from renal tubular acidosis. Several disorders can mimic renal tubular acidosis, and these must be appropriately diagnosed to prevent inadvertent and inappropriate application of alkali therapy. Key physiologic principles and limitations in the assessment of renal acid handling that can pose diagnostic challenges are enumerated.

Details

ISSN :
15485595
Volume :
25
Database :
OpenAIRE
Journal :
Advances in Chronic Kidney Disease
Accession number :
edsair.doi.dedup.....dabc7e0093c55a3af111b154bdf51438
Full Text :
https://doi.org/10.1053/j.ackd.2018.05.001