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Genotoxic repercussion of high‐intensity radiation (x‐rays) on hospital radiographers

Authors :
Haripriya Kuchi Bhotla
Balamuralikrishnan Balasubramanian
Kannan R. R. Rengasamy
Vijaya Anand Arumugam
Karthick Kumar Alagamuthu
Vadivalagan Chithravel
Aditi Chaudhary
Amer M. Alanazi
Manikantan Pappuswamy
Arun Meyyazhagan
Source :
Environmental and Molecular Mutagenesis. 64:123-131
Publication Year :
2022
Publisher :
Wiley, 2022.

Abstract

Recent technological advances in the medical field have increased the plausibility of exposing humans to high-intensity wavelength radiations like x-rays and gamma rays while diagnosing or treating specific medical maladies. These radiations induce nucleotide changes and chromosomal alterations in the exposed population, intentionally or accidentally. A radiological investigation is regularly used in identifying the disease, especially by the technicians working in intensive care units. The current study observes the genetic damages like chromosomal abnormalities (CA) in clinicians who are occupationally exposed to high-intensity radiations (x-rays) at their workplaces using universal cytogenetic tools like micronucleus assay (MN), sister chromatid exchange and comet assay. The study was conducted between 100 exposed practitioners from the abdominal scanning, chest scanning, cranial and orthopedic or bone scanning department and age-matched healthy controls. We observed a slightly higher rate of MN and CA (p .05) in orthopedic and chest department practitioners than in other departments concerning increasing age and duration of exposure at work. Our results emphasize taking extra precautionary measures in clinical and hospital radiation laboratories to protect the practitioners.

Details

ISSN :
10982280 and 08936692
Volume :
64
Database :
OpenAIRE
Journal :
Environmental and Molecular Mutagenesis
Accession number :
edsair.doi.dedup.....db3025ee8a34599dd1505c0a61564192
Full Text :
https://doi.org/10.1002/em.22523