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IARC Monographs : 40 Years of Evaluating Carcinogenic Hazards to Humans
- Source :
- Environmental Health Perspectives, 123(6), 507. Public Health Services, US Dept of Health and Human Services, Pearce, N, Blair, A, Vineis, P, Ahrens, W, Andersen, A, Anto, J M, Armstrong, B K, Baccarelli, A A, Beland, F A, Berrington, A, Bertazzi, P A, Birnbaum, L S, Brownson, R C, Bucher, J R, Cantor, K P, Cardis, E, Cherrie, J W, Christiani, D C, Cocco, P, Coggon, D, Comba, P, Demers, P A, Dement, J M, Douwes, J, Eisen, E A, Engel, L S, Fenske, R A, Fleming, L E, Fletcher, T, Fontham, E, Forastiere, F, Frentzel-Beyme, R, Fritschi, L, Gerin, M, Goldberg, M, Grandjean, P, Grimsrud, T K, Gustavsson, P, Haines, A, Hartge, P, Hansen, J, Hauptmann, M, Heederik, D, Hemminki, K, Hemon, D, Hertz-Picciotto, I, Hoppin, J A, Huff, J, Jarvholm, B, Kang, D, Karagas, M R, Kjaerheim, K, Kjuus, H, Kogevinas, M, Kriebel, D, Kristensen, P, Kromhout, H, Laden, F, Lebailly, P, LeMasters, G, Lubin, J H, Lynch, C F, Lynge, E, 't Mannetje, A, McMichael, A J, McLaughlin, J R, Marrett, L, Martuzzi, M, Merchant, J A, Merler, E, Merletti, F, Miller, A, Mirer, F E, Monson, R, Nordby, K-C, Olshan, A F, Parent, M-E, Perera, F P, Perry, M J, Pesatori, A C, Pirastu, R, Porta, M, Pukkala, E, Rice, C, Richardson, D B, Ritter, L, Ritz, B, Ronckers, C M, Rushton, L, Rusiecki, J A, Rusyn, I, Samet, J M, Sandler, D P, de Sanjose, S, Schernhammer, E, Costantini, A S, Seixas, N, Shy, C, Siemiatycki, J, Silverman, D T, Simonato, L, Smith, A H, Smith, M T, Spinelli, J J, Spitz, M R, Stallones, L, Stayner, L T, Steenland, K, Stenzel, M, Stewart, B W, Stewart, P A, Symanski, E, Terracini, B, Tolbert, P E, Vainio, H, Vena, J, Vermeulen, R, Victora, C G, Ward, E M, Weinberg, C R, Weisenburger, D, Wesseling, C, Weiderpass, E & Zahm, S H 2015, ' IARC Monographs : 40 Years of Evaluating Carcinogenic Hazards to Humans ', Environmental Health Perspectives, vol. 123, no. 6, pp. 507-14 . https://doi.org/10.1289/ehp.1409149, Dipòsit Digital de la UB, Universidad de Barcelona, Environmental health perspectives, 123(6), 507-514. Public Health Services, US Dept of Health and Human Services, Environmental Health Perspectives, Environmental Health Perspectives, National Institute of Environmental Health Sciences, 2015, 123 (6), pp.507-14. ⟨10.1289/ehp.1409149⟩, Environmental health perspectives, 123(6): 507-514, Environmental Health Perspectives, National Institute of Environmental Health Sciences, 2015, 123 (6), pp.507-14. 〈10.1289/ehp.1409149〉, Recercat. Dipósit de la Recerca de Catalunya, instname
- Publication Year :
- 2015
- Publisher :
- Umeå universitet, Yrkes- och miljömedicin, 2015.
-
Abstract
- BACKGROUND: Recently, the International Agency for Research on Cancer (IARC) Programme for the Evaluation of Carcinogenic Risks to Humans has been criticized for several of its evaluations, and also for the approach used to perform these evaluations. Some critics have claimed that failures of IARC Working Groups to recognize study weaknesses and biases of Working Group members have led to inappropriate classification of a number of agents as carcinogenic to humans.OBJECTIVES: The authors of this Commentary are scientists from various disciplines relevant to the identification and hazard evaluation of human carcinogens. We examined criticisms of the IARC classification process to determine the validity of these concerns. Here, we present the results of that examination, review the history of IARC evaluations, and describe how the IARC evaluations are performed.DISCUSSION: We concluded that these recent criticisms are unconvincing. The procedures employed by IARC to assemble Working Groups of scientists from the various disciplines and the techniques followed to review the literature and perform hazard assessment of various agents provide a balanced evaluation and an appropriate indication of the weight of the evidence. Some disagreement by individual scientists to some evaluations is not evidence of process failure. The review process has been modified over time and will undoubtedly be altered in the future to improve the process. Any process can in theory be improved, and we would support continued review and improvement of the IARC processes. This does not mean, however, that the current procedures are flawed.CONCLUSIONS: The IARC Monographs have made, and continue to make, major contributions to the scientific underpinning for societal actions to improve the public's health.CITATION: Pearce N, Blair A, Vineis P, Ahrens W, Andersen A, Anto JM, Armstrong BK, Baccarelli AA, Beland FA, Berrington A, Bertazzi PA, Birnbaum LS, Brownson RC, Bucher JR, Cantor KP, Cardis E, Cherrie JW, Christiani DC, Cocco P, Coggon D, Comba P, Demers PA, Dement JM, Douwes J, Eisen EA, Engel LS, Fenske RA, Fleming LE, Fletcher T, Fontham E, Forastiere F, Frentzel-Beyme R, Fritschi L, Gerin M, Goldberg M, Grandjean P, Grimsrud TK, Gustavsson P, Haines A, Hartge P, Hansen J, Hauptmann M, Heederik D, Hemminki K, Hemon D, Hertz-Picciotto I, Hoppin JA, Huff J, Jarvholm B, Kang D, Karagas MR, Kjaerheim K, Kjuus H, Kogevinas M, Kriebel D, Kristensen P, Kromhout H, Laden F, Lebailly P, LeMasters G, Lubin JH, Lynch CF, Lynge E, 't Mannetje A, McMichael AJ, McLaughlin JR, Marrett L, Martuzzi M, Merchant JA, Merler E, Merletti F, Miller A, Mirer FE, Monson R, Nordby KC, Olshan AF, Parent ME, Perera FP, Perry MJ, Pesatori AC, Pirastu R, Porta M, Pukkala E, Rice C, Richardson DB, Ritter L, Ritz B, Ronckers CM, Rushton L, Rusiecki JA, Rusyn I, Samet JM, Sandler DP, de Sanjose S, Schernhammer E, Seniori Costantini A, Seixas N, Shy C, Siemiatycki J, Silverman DT, Simonato L, Smith AH, Smith MT, Spinelli JJ, Spitz MR, Stallones L, Stayner LT, Steenland K, Stenzel M, Stewart BW, Stewart PA, Symanski E, Terracini B, Tolbert PE, Vainio H, Vena J, Vermeulen R, Victora CG, Ward EM, Weinberg CR, Weisenburger D, Wesseling C, Weiderpass E, Zahm SH. 2015. IARC Monographs: 40 years of evaluating carcinogenic hazards to humans. Environ Health Perspect 123:507-514; http://dx.doi.org/10.1289/ehp.1409149.
- Subjects :
- Pathology
Biomedical Research
Health, Toxicology and Mutagenesis
[SDV]Life Sciences [q-bio]
05 Environmental Sciences
Toxicology
MESH: Carcinogens, Environmental
0302 clinical medicine
CANCER-EPIDEMIOLOGY
Neoplasms
Epidemiology of cancer
PLEA
PROGRAM
Medicine
MESH: Neoplasms
Càncer
health care economics and organizations
Public, Environmental & Occupational Health
Cancer
0303 health sciences
Publications
11 Medical And Health Sciences
MESH : Publications
POLICY
030220 oncology & carcinogenesis
PUBLIC-HEALTH
Public Health
MESH: Public Health
MESH : Biomedical Research
Life Sciences & Biomedicine
International agency
medicine.medical_specialty
MESH : Public Health
education
MESH : International Agencies
Environmental Sciences & Ecology
macromolecular substances
MESH: Publications
MESH : Carcinogens, Environmental
MESH: International Agencies
03 medical and health sciences
Arbetsmedicin och miljömedicin
ADHERENCE
Environmental health
Humans
VDP::Medisinske Fag: 700
030304 developmental biology
Science & Technology
MESH: Humans
[ SDV ] Life Sciences [q-bio]
business.industry
MESH: Biomedical Research
MESH : Humans
Public Health, Environmental and Occupational Health
RECIPE
International Agencies
PRINCIPLES UNDERLYING SCIENCE
Occupational Health and Environmental Health
MESH : Neoplasms
Carcinogens, Environmental
VDP::Medical disciplines: 700
Commentary
business
FALSE
Cancerígens
Environmental Sciences
EPIDEMIOLOGIC ENTERPRISE
Subjects
Details
- Language :
- English
- ISSN :
- 00916765 and 15529924
- Database :
- OpenAIRE
- Journal :
- Environmental Health Perspectives, 123(6), 507. Public Health Services, US Dept of Health and Human Services, Pearce, N, Blair, A, Vineis, P, Ahrens, W, Andersen, A, Anto, J M, Armstrong, B K, Baccarelli, A A, Beland, F A, Berrington, A, Bertazzi, P A, Birnbaum, L S, Brownson, R C, Bucher, J R, Cantor, K P, Cardis, E, Cherrie, J W, Christiani, D C, Cocco, P, Coggon, D, Comba, P, Demers, P A, Dement, J M, Douwes, J, Eisen, E A, Engel, L S, Fenske, R A, Fleming, L E, Fletcher, T, Fontham, E, Forastiere, F, Frentzel-Beyme, R, Fritschi, L, Gerin, M, Goldberg, M, Grandjean, P, Grimsrud, T K, Gustavsson, P, Haines, A, Hartge, P, Hansen, J, Hauptmann, M, Heederik, D, Hemminki, K, Hemon, D, Hertz-Picciotto, I, Hoppin, J A, Huff, J, Jarvholm, B, Kang, D, Karagas, M R, Kjaerheim, K, Kjuus, H, Kogevinas, M, Kriebel, D, Kristensen, P, Kromhout, H, Laden, F, Lebailly, P, LeMasters, G, Lubin, J H, Lynch, C F, Lynge, E, 't Mannetje, A, McMichael, A J, McLaughlin, J R, Marrett, L, Martuzzi, M, Merchant, J A, Merler, E, Merletti, F, Miller, A, Mirer, F E, Monson, R, Nordby, K-C, Olshan, A F, Parent, M-E, Perera, F P, Perry, M J, Pesatori, A C, Pirastu, R, Porta, M, Pukkala, E, Rice, C, Richardson, D B, Ritter, L, Ritz, B, Ronckers, C M, Rushton, L, Rusiecki, J A, Rusyn, I, Samet, J M, Sandler, D P, de Sanjose, S, Schernhammer, E, Costantini, A S, Seixas, N, Shy, C, Siemiatycki, J, Silverman, D T, Simonato, L, Smith, A H, Smith, M T, Spinelli, J J, Spitz, M R, Stallones, L, Stayner, L T, Steenland, K, Stenzel, M, Stewart, B W, Stewart, P A, Symanski, E, Terracini, B, Tolbert, P E, Vainio, H, Vena, J, Vermeulen, R, Victora, C G, Ward, E M, Weinberg, C R, Weisenburger, D, Wesseling, C, Weiderpass, E & Zahm, S H 2015, ' IARC Monographs : 40 Years of Evaluating Carcinogenic Hazards to Humans ', Environmental Health Perspectives, vol. 123, no. 6, pp. 507-14 . https://doi.org/10.1289/ehp.1409149, Dipòsit Digital de la UB, Universidad de Barcelona, Environmental health perspectives, 123(6), 507-514. Public Health Services, US Dept of Health and Human Services, Environmental Health Perspectives, Environmental Health Perspectives, National Institute of Environmental Health Sciences, 2015, 123 (6), pp.507-14. ⟨10.1289/ehp.1409149⟩, Environmental health perspectives, 123(6): 507-514, Environmental Health Perspectives, National Institute of Environmental Health Sciences, 2015, 123 (6), pp.507-14. 〈10.1289/ehp.1409149〉, Recercat. Dipósit de la Recerca de Catalunya, instname
- Accession number :
- edsair.doi.dedup.....db4e6d814a63f341202e8f0f3d8a0beb