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synthesis of N-protected alpha-amino aldehydes from their morpholine amide derivatives
- Source :
- Tetrahedron Letters, Tetrahedron Letters, Elsevier, 2000, 41, pp.37-40. ⟨10.1016/S0040-4039(99)01818-3⟩
- Publication Year :
- 2000
- Publisher :
- HAL CCSD, 2000.
-
Abstract
- A new method for the synthesis of N -protected α-amino aldehydes was developed. N -Protected α-amino amides of morpholine were easily prepared and then reduced with LiAlH 4 to produce clean N -protected α-amino aldehydes. This new scheme of synthesis can be used with Boc, Z and Fmoc amino-protecting groups.
Details
- Language :
- English
- ISSN :
- 00404039
- Database :
- OpenAIRE
- Journal :
- Tetrahedron Letters, Tetrahedron Letters, Elsevier, 2000, 41, pp.37-40. ⟨10.1016/S0040-4039(99)01818-3⟩
- Accession number :
- edsair.doi.dedup.....db5e3adac8676a2f3c99cd5f1ab8cabc