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Prognostic impact of JAK2V617F mutation in myelodysplatic syndromes: A matched case control study

Authors :
Lionel Ades
Véronique Mansat-De Mas
Benoit de Renzis
Zahia Azgui
Laurent Knoops
Odile Beyne-Rauzy
Pierre Fenaux
Aurélie Cabrespine
Jean-Jacques Kiladjian
Eric Wattel
UCL - (SLuc) Service d'hématologie
UCL - SSS/DDUV - Institut de Duve
Source :
Leukemia Research Reports, Leukemia research reports, Vol. 2, no.2, p. 64-66 (2013)
Publisher :
The Authors. Published by Elsevier Ltd.

Abstract

While in RARS-T, JAK2V617F mutation is common and associated with good prognosis, the clinical and prognostic impact of this mutation in other MDS is unknown. We collected data from 132 non-RARS-T MDS with known JAK2V617F mutation status. JAK2V617F mutation was significantly correlated with lower progression to AML (p

Details

Language :
English
ISSN :
22130489
Issue :
2
Database :
OpenAIRE
Journal :
Leukemia Research Reports
Accession number :
edsair.doi.dedup.....dbebd296fe2a2fdc5dc9cc37ce1a95fe
Full Text :
https://doi.org/10.1016/j.lrr.2013.06.003