Back to Search
Start Over
Severe Neonatal Hyperbilirubinemia in the Netherlands
- Source :
- Neonatology, 104(2), 137-142. KARGER
- Publication Year :
- 2013
- Publisher :
- KARGER, 2013.
-
Abstract
- Background: The occurrence of severe neonatal hyperbilirubinemia (SH) is partly attributed to nonhospitalized perinatal care. The Netherlands have a high frequency of home births and nonhospitalized perinatal care, and the incidence of SH is unknown. Objective: To assess the effects of home births and early hospital discharge on the incidence of SH in term-born infants in the Netherlands. Methods: In this nationwide prospective surveillance study between 2005 and 2009, infants (≥37 weeks GA) were included if total serum bilirubin (TSB) was ≥500 µmol/l or if they received an exchange transfusion when TSB was ≥340 µmol/l. Results: Seventy-one infants had SH (incidence 10.4/100,000); 43 had a TSB ≥500 μmol/l (incidence 6.3/100,000) and 45 (63%) underwent an exchange transfusion. 26% of the infants with SH were born at home, which is similar to 22% of all term infants who are born at home in the Netherlands (p = 0.41). Maximum TSB levels were similar in infants born at home (523 ± 114 μmol/l) and infants born in hospital (510 ± 123 μmol/l; p = 0.70). Of the 51 infants born in hospital, 33 were discharged and readmitted with SH, with maximal TSB levels (567 ± 114 μmol/l), which were higher than in infants who remained hospitalized (406 ± 47 μmol/l; p = 0.0001). Conclusion: The incidence of severe hyperbilirubinemia in term-born infants in the Netherlands is 10.4 per 100,000, which is similar to other developed countries. Home birth and early hospital discharge do not necessarily lead to a higher incidence of SH, provided that perinatal home care is well organized.
- Subjects :
- Pediatrics
medicine.medical_specialty
Time Factors
Monitoring
KERNICTERUS
Bilirubin
medicine.medical_treatment
Exchange Transfusion, Whole Blood
Exchange transfusion
Gestational Age
Severity of Illness Index
chemistry.chemical_compound
Severity of illness
Medicine
Humans
Prospective Studies
Registries
Prospective cohort study
Home health care
Home Childbirth
Netherlands
Hyperbilirubinemia
NEAR-TERM INFANTS
Chi-Square Distribution
Surveillance
business.industry
Incidence (epidemiology)
Incidence
Infant, Newborn
Gestational age
medicine.disease
Patient Discharge
Perinatal Care
chemistry
BILIRUBIN
Pediatrics, Perinatology and Child Health
DENMARK
Kernicterus
Hyperbilirubinemia, Neonatal
business
Home birth
Biomarkers
Developmental Biology
NEWBORN
Subjects
Details
- Language :
- English
- ISSN :
- 16617800
- Volume :
- 104
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Neonatology
- Accession number :
- edsair.doi.dedup.....dcccb550627aedf0afe12062cd952699