Back to Search
Start Over
Effect of kami-kihi-to (jia-wei-gui-pi-tang) for experimental osteopenia
- Source :
- The American journal of Chinese medicine. 33(1)
- Publication Year :
- 2005
-
Abstract
- In order to examine the effects of Kami-kihi-to (KKT or Jia-Wei-Gui-Pi-Tang) on osteopenia, we measured bone mineral density using computed X-ray absorptometry and monitored metabolism and bone tissue in an ovariectomized (OVX) rat model. Bone mineral density was significantly lower in the OVX group than in normal group 3 months after ovariectomy. However, the bone mineral density of the OVX group administered KKT was clearly higher than that of the untreated OVX group. Locomotor activity was regular in the normal group and in the OVX groups before administration of KKT. After 6-month administration of KKT, in OVX groups, the pattern of locomotor activity became diphasic with clear active and resting phases, as was also observed in the normal group. The locomotor activity did not decrease in the OVX groups after administration of KKT. At 6 months, the continuity of the trabecular bone was higher in the OVX group administered KKT than in the untreated OVX group. These results indicate that KKT improved the menopausal symptoms and increased the locomotor activity of the OVX group, thereby increasing bone mineral density.
- Subjects :
- endocrine system
medicine.medical_specialty
Ovariectomy
Rat model
Dentistry
Motor Activity
Bone tissue
Locomotor activity
Bone Density
Internal medicine
polycyclic compounds
Pi
Medicine
Animals
Rats, Wistar
Bone mineral
business.industry
General Medicine
medicine.disease
Rats
Osteopenia
Trabecular bone
Bone Diseases, Metabolic
surgical procedures, operative
medicine.anatomical_structure
Endocrinology
Complementary and alternative medicine
Ovariectomized rat
Osteoporosis
Female
business
hormones, hormone substitutes, and hormone antagonists
Drugs, Chinese Herbal
Subjects
Details
- ISSN :
- 0192415X
- Volume :
- 33
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- The American journal of Chinese medicine
- Accession number :
- edsair.doi.dedup.....dd1d34e69c258f231b0b2df4c77a0251