Back to Search
Start Over
Fiducial detection and registration for 3D IMRT QA with organ‐specific dose information
- Source :
- Journal of Applied Clinical Medical Physics
- Publication Year :
- 2021
- Publisher :
- Wiley, 2021.
-
Abstract
- Purpose Two‐dimensional (2D) IMRT QA has been widely performed in Radiation Oncology clinic. However, concerns regarding its sensitivity in detecting delivery errors and its clinical meaning have been raised in publications. In this study, a robust methodology of three‐dimensional (3D) IMRT QA using fiducial registration and structure‐mapping was proposed to acquire organ‐specific dose information. Methods Computed tomography (CT) markers were placed on the PRESAGE dosimeter as fiducials before CT simulation. Subsequently, the images were transferred to the treatment planning system to create a verification plan for the examined treatment plan. Patient’s CT images were registered to the CT images of the dosimeter for structure mapping according to the positions of the fiducials. After irradiation, the 3D dose distribution was read‐out by an optical‐CT (OCT) scanner with fiducials shown on the OCT dose images. An automatic localization algorithm was developed in MATLAB to register the markers in the OCT images to those in the CT images of the dosimeter. SlicerRT was used to show and analyze the results. Fiducial registration error was acquired by measuring the discrepancies in 20 fiducial registrations, and thus the fiducial localization error and target registration error (TRE) was estimated. Results Dosimetry comparison between the calculated and measured dose distribution in various forms were presented, including 2D isodose lines comparison, 3D isodose surfaces with patient’s anatomical structures, 2D and 3D gamma index, dose volume histogram and 3D view of gamma failing points. From the analysis of 20 fiducial registrations, fiducial registration error was measured to be 0.62 mm and fiducial localization error was calculated to be 0.44 mm. Target registration uncertainty of the proposed methodology was estimated to be within 0.3 mm in the area of dose measurement. Conclusions This study proposed a robust methodology of 3D measurement‐based IMRT QA for organ‐specific dose comparison and demonstrated its clinical feasibility.
- Subjects :
- Scanner
Dose-volume histogram
3D IMRT QA
Computer science
030218 nuclear medicine & medical imaging
03 medical and health sciences
0302 clinical medicine
Fiducial Markers
Radiation oncology
Organ specific
Humans
Radiation Oncology Physics
Dosimetry
Radiology, Nuclear Medicine and imaging
Radiometry
Radiation treatment planning
Instrumentation
Radiation
Dosimeter
business.industry
030220 oncology & carcinogenesis
Radiotherapy, Intensity-Modulated
Tomography, X-Ray Computed
Nuclear medicine
business
Fiducial marker
Algorithms
Subjects
Details
- ISSN :
- 15269914
- Volume :
- 22
- Database :
- OpenAIRE
- Journal :
- Journal of Applied Clinical Medical Physics
- Accession number :
- edsair.doi.dedup.....dd2242f50271aac60312af89dfd3c729