Back to Search Start Over

Verifying the Benefits of Radical Treatment in Posttransplant Hepatocellular Carcinoma Oligo‐recurrence: A Propensity Score Analysis

Authors :
James Fung
Kin Pan Au
Albert C. Y. Chan
Kenneth S. H. Chok
Wing Chiu Dai
Chung Mau Lo
Source :
Liver Transplantation. 28:51-64
Publication Year :
2021
Publisher :
Ovid Technologies (Wolters Kluwer Health), 2021.

Abstract

This study verified whether radical treatment for hepatocellular carcinoma (HCC) oligo-recurrence after liver transplantation conveys survival benefits. A retrospective study of 144 patients with posttransplant HCC recurrence was performed. Propensity score matching was performed to adjust for baseline covariates between patients who received radical and palliative treatments. The primary endpoint was postrecurrence survival. A total of 50 patients (35%) received radical treatment for recurrence, and 76 (53%) and 18 (13%) patients received palliative and supportive treatments, respectively. Compared with the radical group, patients who received palliative treatment had more early recurrences (time from transplant 17 versus 11 months; P = 0.01) and more extensive disease in terms of tumor numbers (1 versus 4; P

Details

ISSN :
15276473 and 15276465
Volume :
28
Database :
OpenAIRE
Journal :
Liver Transplantation
Accession number :
edsair.doi.dedup.....dd2dce8ce345a1715156a8b95c9ede0e
Full Text :
https://doi.org/10.1002/lt.26251