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Verifying the Benefits of Radical Treatment in Posttransplant Hepatocellular Carcinoma Oligo‐recurrence: A Propensity Score Analysis
- Source :
- Liver Transplantation. 28:51-64
- Publication Year :
- 2021
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2021.
-
Abstract
- This study verified whether radical treatment for hepatocellular carcinoma (HCC) oligo-recurrence after liver transplantation conveys survival benefits. A retrospective study of 144 patients with posttransplant HCC recurrence was performed. Propensity score matching was performed to adjust for baseline covariates between patients who received radical and palliative treatments. The primary endpoint was postrecurrence survival. A total of 50 patients (35%) received radical treatment for recurrence, and 76 (53%) and 18 (13%) patients received palliative and supportive treatments, respectively. Compared with the radical group, patients who received palliative treatment had more early recurrences (time from transplant 17 versus 11 months; P = 0.01) and more extensive disease in terms of tumor numbers (1 versus 4; P
- Subjects :
- medicine.medical_specialty
Carcinoma, Hepatocellular
medicine.medical_treatment
Immunology
Liver transplantation
Gastroenterology
Risk Factors
Interquartile range
Internal medicine
medicine
Clinical endpoint
Humans
Propensity Score
Retrospective Studies
Transplantation
Hepatology
Proportional hazards model
business.industry
Liver Neoplasms
Hazard ratio
Prognosis
medicine.disease
Liver Transplantation
Hepatocellular carcinoma
Propensity score matching
Surgery
alpha-Fetoproteins
Neoplasm Recurrence, Local
Liver cancer
business
Subjects
Details
- ISSN :
- 15276473 and 15276465
- Volume :
- 28
- Database :
- OpenAIRE
- Journal :
- Liver Transplantation
- Accession number :
- edsair.doi.dedup.....dd2dce8ce345a1715156a8b95c9ede0e
- Full Text :
- https://doi.org/10.1002/lt.26251