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In vitro susceptibility of Helicobacter pylori to protolichesterinic acid from the lichen Cetraria islandica
- Source :
- Scopus-Elsevier
-
Abstract
- With reference to the traditional use of Cetraria islandica (Iceland moss) for relief of gastric and duodenal ulcer, plant extracts were screened for in vitro activity against Helicobacter pylori. (+)-Protolichesterinic acid, an aliphatic alpha-methylene-gamma-lactone, was identified as an active component. The MIC range of protolichesterinic acid, in free as well as salt form, was 16 to 64 micrograms/ml.
- Subjects :
- Pharmacology
biology
Helicobacter pylori
Lichens
Plant Extracts
Spirillaceae
Cetraria
Biological activity
Microbial Sensitivity Tests
Pharmacognosy
biology.organism_classification
Iceland moss
Microbiology
Infectious Diseases
4-Butyrolactone
Pharmacology (medical)
Bacteria
Antibacterial agent
Research Article
Subjects
Details
- Database :
- OpenAIRE
- Journal :
- Scopus-Elsevier
- Accession number :
- edsair.doi.dedup.....dd5a62936e7799be37f45e551fec4d4e