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Molecular evolution and expression of oxygen transport genes in livebearing fishes (Poeciliidae) from hydrogen sulfide rich springs
- Source :
- Genome. 61:273-286
- Publication Year :
- 2018
- Publisher :
- Canadian Science Publishing, 2018.
-
Abstract
- Hydrogen sulfide (H2S) is a natural toxicant in some aquatic environments that has diverse molecular targets. It binds to oxygen transport proteins, rendering them non-functional by reducing oxygen-binding affinity. Hence, organisms permanently inhabiting H2S-rich environments are predicted to exhibit adaptive modifications to compensate for the reduced capacity to transport oxygen. We investigated 10 lineages of fish of the family Poeciliidae that have colonized freshwater springs rich in H2S—along with related lineages from non-sulfidic environments—to test hypotheses about the expression and evolution of oxygen transport genes in a phylogenetic context. We predicted shifts in the expression of and signatures of positive selection on oxygen transport genes upon colonization of H2S-rich habitats. Our analyses indicated significant shifts in gene expression for multiple hemoglobin genes in lineages that have colonized H2S-rich environments, and three hemoglobin genes exhibited relaxed selection in sulfidic compared to non-sulfidic lineages. However, neither changes in gene expression nor signatures of selection were consistent among all lineages in H2S-rich environments. Oxygen transport genes may consequently be predictable targets of selection during adaptation to sulfidic environments, but changes in gene expression and molecular evolution of oxygen transport genes in H2S-rich environments are not necessarily repeatable across replicated lineages.
- Subjects :
- Fish Proteins
0106 biological sciences
0301 basic medicine
Hydrogen sulfide
chemistry.chemical_element
Fresh Water
Biology
010603 evolutionary biology
01 natural sciences
Oxygen
Evolution, Molecular
Cyprinodontiformes
03 medical and health sciences
chemistry.chemical_compound
Molecular evolution
Genetics
Animals
Hydrogen Sulfide
Mexico
Molecular Biology
Gene
Ecosystem
Phylogeny
Poeciliidae
Geography
Gene Expression Profiling
Aquatic ecosystem
Dominican Republic
Oxygen transport
Membrane Transport Proteins
General Medicine
biology.organism_classification
Adaptation, Physiological
030104 developmental biology
chemistry
Environmental chemistry
Florida
Biotechnology
Toxicant
Subjects
Details
- ISSN :
- 14803321 and 08312796
- Volume :
- 61
- Database :
- OpenAIRE
- Journal :
- Genome
- Accession number :
- edsair.doi.dedup.....dde8cb2599ed9b2c584a91202e2aae83