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Responsiveness of the EQ-5D and 8-item Parkinson’s Disease Questionnaire (PDQ-8) in a 4-year follow-up study
- Source :
- Quality of Life Research. 19:565-569
- Publication Year :
- 2010
- Publisher :
- Springer Science and Business Media LLC, 2010.
-
Abstract
- The purpose of this study was to evaluate the responsiveness of the EQ-5D and the Parkinson’s Disease Questionnaire (PDQ-8) to deterioration in health-related quality of life (HRQoL) in patients with Parkinson’s disease (PD). HRQoL and clinical data collected from 31 patients with PD (male: 74.2%, mean age: 61 years) who were surveyed with the EQ-5D and the PDQ-8 questionnaires in 2002 and 2006/2007 were analyzed. Responsiveness of the EQ-5D, PDQ-8, and Hoehn and Yahr (H&Y) staging were assessed according to Cohen’s effect size (ES) and standardized response mean (SRM). The mean (standard deviation) EQ-5D index and PDQ-8 summary index (PDQ-8SI) scores were 0.76 (0.23) and 17.7 (14.2) at baseline and 0.52 (0.33) and 35.1 (17.4) at year four. Based on both ES and SRM indices, the rank order of responsiveness of the studied measures, from high to low, was PDQ-8SI (ES = 1.22), EQ-5D index score (ES = 1.06), H&Y score (ES = 0.82), and the EQ-VAS score (ES = 0.24). Both the EQ-5D and PDQ-8 are responsive to changes in health burden of the Parkinson’s disease over a 4-year period.
- Subjects :
- Male
medicine.medical_specialty
Parkinson's disease
Psychometrics
Quality of life
EQ-5D
Surveys and Questionnaires
Adaptation, Psychological
Humans
Medicine
In patient
Prospective Studies
Prospective cohort study
Pain Measurement
business.industry
Public Health, Environmental and Occupational Health
Follow up studies
Parkinson Disease
Middle Aged
medicine.disease
humanities
Index score
Disease Progression
Quality of Life
Physical therapy
Female
business
human activities
Stress, Psychological
Subjects
Details
- ISSN :
- 15732649 and 09629343
- Volume :
- 19
- Database :
- OpenAIRE
- Journal :
- Quality of Life Research
- Accession number :
- edsair.doi.dedup.....de4bab87e75399ce7de0c754e677d225