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Combined Central Retinal Artery and Vein Occlusion Associated with Factor V Leiden Mutation and Treated with Hyperbaric Oxygen
Combined Central Retinal Artery and Vein Occlusion Associated with Factor V Leiden Mutation and Treated with Hyperbaric Oxygen
- Source :
- Case Reports in Ophthalmology, Case Reports in Ophthalmology, Vol 6, Iss 3, Pp 462-468 (2015)
- Publication Year :
- 2015
- Publisher :
- S. Karger AG, 2015.
-
Abstract
- Background: Combined central retinal artery occlusion (CRAO) and central retinal vein occlusion (CRVO) is an uncommon retinal vascular disease which causes sudden visual acuity loss and is associated with poor prognosis and the development of severe complications. We report a very rare case of combined CRAO and CRVO in a patient with factor V Leiden (FVL) mutation (only 3 cases published). To our knowledge, this is the first case of combined CRAO and CRVO treated with hyperbaric oxygen therapy (HBOT). Case and Results: A 49-year-old woman presented with complaints of sudden loss of vision in her left eye (LE), with best corrected visual acuity (BCVA) of 1/20. A complete ophthalmic evaluation with fundus angiography showed combined CRAO and CRVO. The patient was urgently treated with HBOT (she completed a total of 9 sessions in 7 days), with marked visual acuity and angiographic improvement (BCVA of 10/10). Forty-five days later, she developed a new LE CRVO, and BCVA decreased to 5/10 and later to Conclusions: Combined CRAO and CRVO in young adults should be investigated thoroughly for embolic sources, thrombophilic disorders and local ocular conditions. This is the first case of this severe disease that was treated with HBOT, and the visual result was very good.
- Subjects :
- medicine.medical_specialty
Central retinal artery
Visual acuity
genetic structures
Retinal Artery Occlusion
Published online: December, 2015
Fundus (eye)
Retinal vein occlusion
03 medical and health sciences
0302 clinical medicine
lcsh:Ophthalmology
Central retinal vein occlusion
Hyperbaric oxygen therapy
medicine.artery
medicine
Factor V Leiden
Retinal artery occlusion
business.industry
medicine.disease
eye diseases
Vein occlusion
3. Good health
Surgery
Ophthalmology
lcsh:RE1-994
030221 ophthalmology & optometry
Central retinal artery occlusion
medicine.symptom
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 16632699
- Volume :
- 6
- Database :
- OpenAIRE
- Journal :
- Case Reports in Ophthalmology
- Accession number :
- edsair.doi.dedup.....de4c1076a82706a9d151337264a6aa76
- Full Text :
- https://doi.org/10.1159/000442788