Back to Search Start Over

Outcomes of pathologic stage T3a renal cell carcinoma up-staged from small renal tumor: emphasis on partial nephrectomy

Authors :
Seok-Soo Byun
Sung Kyu Hong
Minseung Lee
Cheol Kwak
Hyeon Hoe Kim
Sang Eun Lee
Hakmin Lee
Source :
BMC Cancer, Vol 18, Iss 1, Pp 1-7 (2018), BMC Cancer
Publication Year :
2018
Publisher :
BMC, 2018.

Abstract

Background The prognosis of patients with pathologic stage T3a renal cell carcinoma (RCC) that is up-staged from a small renal tumor remains controversial. We evaluated the prognosis of patients with RCC who were up-staged from clinical stage T1 to pathologic stage T3a. Methods We retrospectively reviewed the data of 3431 patients who were surgically treated for clinical stage T1 RCC. The survival outcomes were compared using Kaplan-Meier and Cox proportional analyses. Results Among the clinical stage T1 patients, 215 (6.3%) were finally up-staged to pathologic stage T3a. Patient age (HR 1.302, 95% CI 1.018–1.046, p 0.5). Conclusions Patients up-staged from clinical stage T1 to pathologic stage T3a RCC showed shorter survival outcomes than those without upstaging. However, partial nephrectomy, compared with radical nephrectomy, showed comparable outcomes in patients who were up-staged.

Details

Language :
English
ISSN :
14712407
Volume :
18
Issue :
1
Database :
OpenAIRE
Journal :
BMC Cancer
Accession number :
edsair.doi.dedup.....de4e3b785f09bcc28704381f4f0d6d2f
Full Text :
https://doi.org/10.1186/s12885-018-4338-1