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Improving Pharmaceutical Innovation By Building A More Comprehensive Database On Drug Development And Use
Improving Pharmaceutical Innovation By Building A More Comprehensive Database On Drug Development And Use
- Source :
- Health Affairs. 34:319-327
- Publication Year :
- 2015
- Publisher :
- Health Affairs (Project Hope), 2015.
-
Abstract
- New drugs and biologics have had a tremendous impact on the treatment of many diseases. However, available measures suggest that pharmaceutical innovation has remained relatively flat, despite substantial growth in research and development spending. We review recent literature on pharmaceutical innovation to identify limitations in measuring and assessing innovation, and we describe the framework and collaborative approach we are using to develop more comprehensive, publicly available metrics for innovation. Our research teams at the Brookings Institution and Deerfield Institute are collaborating with experts from multiple areas of drug development and regulatory review to identify and collect comprehensive data elements related to key development and regulatory characteristics for each new molecular entity approved over the past several decades in the United States and the European Union. Subsequent phases of our effort will add data on downstream product use and patient outcomes and will also include drugs that have failed or been abandoned in development. Such a database will enable researchers to better analyze the drivers of drug innovation, trends in the output of new medicines, and the effect of policy efforts designed to improve innovation.
- Subjects :
- Knowledge management
Drug Industry
Databases, Pharmaceutical
business.industry
Health Policy
United States
Pharmacy Research
Drug development
New chemical entity
Product Surveillance, Postmarketing
Humans
Technology, Pharmaceutical
media_common.cataloged_instance
Operations management
European Union
Product (category theory)
Cooperative Behavior
European union
business
Drug Approval
media_common
Downstream (petroleum industry)
Subjects
Details
- ISSN :
- 15445208 and 02782715
- Volume :
- 34
- Database :
- OpenAIRE
- Journal :
- Health Affairs
- Accession number :
- edsair.doi.dedup.....de8cb1258f73ffedbdc58c7c61b7c4a4
- Full Text :
- https://doi.org/10.1377/hlthaff.2014.1019