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Infiltrating Epitheliosis of the Breast: Fine Needle Aspiration Cytology
Infiltrating Epitheliosis of the Breast: Fine Needle Aspiration Cytology
- Source :
- International journal of surgical pathology. 28(1)
- Publication Year :
- 2019
-
Abstract
- Epitheliosis (or usual duct hyperplasia) is a proliferation of epithelial and myoepithelial cells located within enlarged acini and small ducts, which is characterized by irregular and peripheral fenestration. Infiltrating epitheliosis (IE) is a specific lesion, characterized by classical epitheliosis flowing out into the adjacent stroma. The stroma is desmoplastic and shows keloid appearance with irregular elastosis. IE can mimic malignancy both on radiological and histological grounds. The aim of the present study is to describe the fine needle aspiration cytological features of 6 consecutive cases of IE, with histological correlation. IE cases presenting as screen detected lesions and preoperatively diagnosed on fine needle aspiration cytology (FNAC) were reviewed. All patients had radiologically breast lesions suspicious for malignancy that underwent FNAC followed by surgical resection. The FNAC smears presented some features that could lead to a misdiagnosis of malignancy, such as bloody background, high cellularity, and stromal fragments containing epithelial cells. Nevertheless, malignancy was excluded, due to the absence of atypia and the presence of myoepithelial cells in the cell clusters. IE presents a special FNAC pattern that can be misinterpreted as malignancy. Therefore, knowledge is necessary to avoid patient overtreatment.
- Subjects :
- Adult
Pathology
medicine.medical_specialty
infiltrating epitheliosis
fine needle aspiration cytology
Biopsy, Fine-Needle
Pathology and Forensic Medicine
03 medical and health sciences
Breast Diseases
0302 clinical medicine
Fine needle aspiration cytology
Cytology
medicine
Humans
Breast
skin and connective tissue diseases
Aged
Cell Proliferation
Aged, 80 and over
Hyperplasia
business.industry
Myoepithelial cell
Epithelial Cells
Middle Aged
030224 pathology
medicine.disease
030220 oncology & carcinogenesis
cytology
Surgery
Female
Anatomy
business
Subjects
Details
- ISSN :
- 19402465
- Volume :
- 28
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- International journal of surgical pathology
- Accession number :
- edsair.doi.dedup.....df6d20dfe1595e3f4d9365310df7c3ba