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Psychological morbidity in pemphigus patients in clinical remission and its relation with clinico‐demographic parameters
- Source :
- JDDG: Journal der Deutschen Dermatologischen Gesellschaft. 20:26-33
- Publication Year :
- 2021
- Publisher :
- Wiley, 2021.
-
Abstract
- Background and objectives Significant psychological morbidity exists in patients with active pemphigus. Pemphigus being a chronic disease, psychological morbidity may exist in pemphigus patients in remission as well. The objectives of the study were to assess the psychological morbidity in pemphigus patients in clinical remission and to correlate it with clinico-demographic parameters. Patients and methods Pemphigus patients in clinical remission were consecutively included and were asked to respond to the Hindi/English version of Patient Health Questionnaire (PHQ-9), Generalized Anxiety Disorder (GAD-7) and panic disorder module of PHQ. Results Of 107 patients recruited, 41 (38.3 %, 95 % CI: 29.1-48.2 %) patients were found to have either depression (33 [30.8 %, 95 % CI: 22.2-40.5 %]) or anxiety (38 [35.5 %, 95 % CI: 26.5-45.4 %] syndrome based on cut-offs of PHQ-9 score and GAD-7 score, respectively. Number of patients with mild, moderate and moderately severe/severe depression syndrome were 26 (24.3 %, 95 % CI: 17.2-33.2 %), 7 (6.5 %, 95 % CI: 0.3-12.9 %) and 0 respectively and patients with mild, moderate, severe anxiety syndrome were 29 (27.1 %, 95 % CI: 19.6-36.2 %), 9 (8.4 %, 95 % CI: 4.5-15.2 %) and 0 respectively. Patients with anxiety or depression syndrome had significantly higher clinical disease activity in the past, number of days spent in dermatology inpatient and significantly shorter clinical remission at the time of assessment as compared to those without these symptoms. Conclusions Significant burden of mild/moderate depression or anxiety syndrome associated with past severity of disease and shorter duration of clinical remission was found.
- Subjects :
- Inpatients
medicine.medical_specialty
Generalized anxiety disorder
Depression
business.industry
Panic disorder
Dermatology
Disease
Anxiety
medicine.disease
Patient Health Questionnaire
Pemphigus
Internal medicine
medicine
Humans
In patient
Morbidity
medicine.symptom
business
Depression (differential diagnoses)
Subjects
Details
- ISSN :
- 16100387 and 16100379
- Volume :
- 20
- Database :
- OpenAIRE
- Journal :
- JDDG: Journal der Deutschen Dermatologischen Gesellschaft
- Accession number :
- edsair.doi.dedup.....dfee3bb1dd9d7840ab979b6c819d4fec