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Continuous Glucose Monitoring in Diabetic Women Following Antenatal Corticosteroid Therapy: A Pilot Study
- Source :
- American Journal of Perinatology. 29:335-338
- Publication Year :
- 2011
- Publisher :
- Georg Thieme Verlag KG, 2011.
-
Abstract
- To compare the timing, duration, and severity of corticosteroid-associated hyperglycemia in pregnant women with and without diabetes mellitus (DM). An observational study was conducted of pregnant women with DM and controls who received corticosteroids. Median glucose levels were calculated over 4-hour intervals after the first dose of corticosteroid with a continuous glucose monitor. A glucose level increase of at least 15% above baseline was considered significant. Nine pregnant women participated in this study (six with DM and three without DM). Elevations of glucose levels occurred at hour 20, 44, and 68 in both groups and lasted for up to 4 hours. In those with DM, glucose levels increased 33 to 48%, whereas in those without DM, glucose levels rose 16 to 33%. Several, relatively short episodes of glucose elevation occur in response to corticosteroids, and are more pronounced in diabetic women.
- Subjects :
- Adult
Blood Glucose
medicine.medical_specialty
medicine.drug_class
Pregnancy in Diabetics
Pilot Projects
Betamethasone
Fetal Organ Maturity
Pregnancy
Internal medicine
Diabetes mellitus
Diabetes Mellitus
medicine
Humans
Hypoglycemic Agents
Insulin
Prospective Studies
Prospective cohort study
Glucocorticoids
Lung
Monitoring, Physiologic
Continuous glucose monitoring
business.industry
Case-control study
Obstetrics and Gynecology
Antenatal corticosteroid
medicine.disease
Endocrinology
Case-Control Studies
Hyperglycemia
Pediatrics, Perinatology and Child Health
Corticosteroid
Female
business
Subjects
Details
- ISSN :
- 10988785 and 07351631
- Volume :
- 29
- Database :
- OpenAIRE
- Journal :
- American Journal of Perinatology
- Accession number :
- edsair.doi.dedup.....e0765cc801910c0ff88458089950274b