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A chimeric antigen receptor against prostate-specific membrane antigen, a tumor vasculature target

Authors :
Daniel J. Powell
Soorin Kim
George Coukos
Stephen Santoro
Dimitrios Alatzoglou
Source :
Journal for Immunotherapy of Cancer
Publisher :
Springer Nature

Abstract

Meeting abstracts The tumor endothelium plays a complex role in cancer development. Aberrant blood vessels provide structural support for the tumor, a barrier to immune infiltration, and also serve as a source of pro-tumorigenic signals. In accordance with their atypical function, surface protein

Details

Language :
English
ISSN :
20511426
Volume :
1
Issue :
Suppl 1
Database :
OpenAIRE
Journal :
Journal for ImmunoTherapy of Cancer
Accession number :
edsair.doi.dedup.....e117f03d88c35c01557d49fee9ccc3ee
Full Text :
https://doi.org/10.1186/2051-1426-1-s1-p33