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L-carnitine ameliorated weight loss in fasting therapy: A propensity score-matched study
- Source :
- Complementary Therapies in Medicine. 44:162-165
- Publication Year :
- 2019
- Publisher :
- Elsevier BV, 2019.
-
Abstract
- l -carnitine infusion has been proven to reduce fasting-induced fatigue and hunger in patients with metabolic syndrome in our former study. However, the association between l -carnitine and clinical outcomes of fasting therapy is yet to be investigated. In this study, data from 192 patients who finished fasting therapy from September 2008 to July 2018 were reviewed, among which 142 patients received l -carnitine infusion in fasting regimen. Propensity matching was used to overcome retrospective bias. Patients’ anthropometric measurements and metabolic markers were evaluated. After propensity matching, 40 patients were included in each group. Weight (-4.05 ± 1.65 kg vs -3.25 ± 1.68 kg, P = 0.031) and BMI (-1.51±0.61 kg/m2 vs -1.20 ± 0.62 kg/m2, P = 0.036) decreased in both groups, but significantly more in l -carnitine group, while diastolic blood pressure (-1.67±9.82 mmHg vs -6.21±8.83 mmHg, P = 0.043) and triglycerides (-0.18±0.63 mmol/L vs -1.05±1.70 mmol/L, P = 0.007) decreased significantly more in non- l -carnitine group compared between groups, blood glucose did not differ significantly between groups. l -carnitine can boost the positive effects of fasting therapy on weight loss and maintain the stability of blood pressure.
- Subjects :
- Adult
Blood Glucose
Male
Complementary and Manual Therapy
medicine.medical_specialty
food.diet
Blood Pressure
Gastroenterology
03 medical and health sciences
0302 clinical medicine
food
Weight loss
Carnitine
Internal medicine
Weight Loss
medicine
Humans
030212 general & internal medicine
Propensity Score
Triglycerides
Retrospective Studies
Metabolic Syndrome
Advanced and Specialized Nursing
business.industry
Fasting
Middle Aged
Anthropometry
medicine.disease
Very low calorie diet
Regimen
Blood pressure
Complementary and alternative medicine
Propensity score matching
Female
Metabolic syndrome
medicine.symptom
business
Biomarkers
030217 neurology & neurosurgery
medicine.drug
Subjects
Details
- ISSN :
- 09652299
- Volume :
- 44
- Database :
- OpenAIRE
- Journal :
- Complementary Therapies in Medicine
- Accession number :
- edsair.doi.dedup.....e18b852ae14da17110d9afdcf8918600